DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2224 and csn-5

DIOPT Version :9

Sequence 1:	NP_001263108.1	Gene:	CG2224 / 43617	FlyBaseID:	FBgn0039773	Length:	420	Species:	Drosophila melanogaster
Sequence 2:	NP_500841.1	Gene:	csn-5 / 177342	WormBaseID:	WBGene00000817	Length:	368	Species:	Caenorhabditis elegans

Alignment Length:	204	Identity:	53/204 - (25%)
Similarity:	85/204 - (41%)	Gaps:	44/204 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   223 NSKPSFDRNQKPSYNRTDSLLAGSLRLVYVPGDTMEVFLKLAL-ANTSKNIETCGVLAGHLSQNQ 286
            |:|| :|::  |.|.:...:.|.:|             ||:.: |....|:|..|:|.|.:..|.
Worm    42 NAKP-WDKD--PHYFKQIKISAIAL-------------LKMTMHAKRGGNLEIMGLLQGRIDANS 90

  Fly   287 LYITHIITPQQQGTPDSCN---------TMHEEQIFDVQDQMQLITLGWIHTHPTQTAFLSSVDL 342
            ..|..:.....:||....|         |::.| :.|.:.:.:.: :||.|:||....:||.:|:
Worm    91 FIILDVFALPVEGTETRVNAQAQAYEYMTVYSE-MCDTEGRKEKV-VGWYHSHPGYGCWLSGIDV 153

  Fly   343 HTHCSYQIMMPEALAIVCAPKYNTTGFFILTPHYGLDYIAQCR--QSGFHPHPNDPPLFMEAQHI 405
            .|....|......:|||..|        :.|...|...|...|  ..|:.| |:|.|  .|.|.|
Worm   154 STQTLNQKFQEPWVAIVIDP--------LRTMSAGKVDIGAFRTYPEGYRP-PDDVP--SEYQSI 207

  Fly   406 RMDNQAKIK 414
            .:   |||:
Worm   208 PL---AKIE 213

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2224	NP_001263108.1	USP8_dimer	16..119	CDD:286108
CG2224	NP_001263108.1	MPN_AMSH_like	247..419	CDD:163697	46/180 (26%)
csn-5	NP_500841.1	MPN_RPN11_CSN5	45..292	CDD:163700	51/201 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1310
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810