| Sequence 1: | NP_001247368.1 | Gene: | aralar1 / 43616 | FlyBaseID: | FBgn0028646 | Length: | 707 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_003696.2 | Gene: | SLC25A12 / 8604 | HGNCID: | 10982 | Length: | 678 | Species: | Homo sapiens |
| Alignment Length: | 683 | Identity: | 395/683 - (57%) |
|---|---|---|---|
| Similarity: | 505/683 - (73%) | Gaps: | 31/683 - (4%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 28 KRAGTEKLREVFLKYASIQKNGEHYMTSEDFVRKFLGLFSESAFNDESVRLLANIADTSKDGLIS 92
Fly 93 FSEFQAFEGLLCTPDALYRTAFQLFDRKGNGTVSYADFADVVQKTELHSKIPFSLDGPFIKRYFG 157
Fly 158 DKKQRLINYAEFTQLLHDFHEEHAMEAFRSKDPAGTGFISPLDFQDIIVNVKRHLLTPGVRDNLV 222
Fly 223 SVTEG---HKVSFPYFIAFTSLLNNMELIKQVYLHATEGSRTDM-ITKDQILLAAQTMSQITPLE 283
Fly 284 IDILFHLAGAVHQAGWWKRRRKIPPSSRIDYSDLSNIAPEHYTKHMTHRLAEIKAVESPA-DRSA 347
Fly 348 FIQVLESSYRFTLGSFAGAVGATVVYPIDLVKTRMQNQR-AGSYIGEVAYRNSWDCFKKVVRHEG 411
Fly 412 FMGLYRGLLPQLMGVAPEKAIKLTVNDLVRDKLTDKKGNIPTWAEVLAGGCAGASQVVFTNPLEI 476
Fly 477 VKIRLQVAGEIASGSKIRAWSVVRELGLFGLYKGARACLLRDVPFSAIYFPTYAHTKAMMADKDG 541
Fly 542 YNHPLTLLAAGAIAGVPAASLVTPADVIKTRLQVVARSGQTTYTGVWDATKKIMAEEGPRAFWKG 606
Fly 607 TAARVFRSSPQFGVTLVTYELLQRLFYVDFGGTQPKGSEAHKITTPLEQAAASVTTENVDHIGGY 671
Fly 672 RAAVPLLAGVESKFGLYLPRFGRGVTAASPSTA 704 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| aralar1 | NP_001247368.1 | EF-hand_7 | 35..99 | CDD:290234 | 34/63 (54%) |
| EF-hand_8 | 51..99 | CDD:290545 | 25/47 (53%) | ||
| EF-hand_7 | 81..134 | CDD:290234 | 27/52 (52%) | ||
| EFh | 84..135 | CDD:298682 | 26/50 (52%) | ||
| EF-hand_7 | 111..173 | CDD:290234 | 26/61 (43%) | ||
| Mito_carr | 350..448 | CDD:278578 | 77/98 (79%) | ||
| PTZ00169 | 358..631 | CDD:240302 | 210/273 (77%) | ||
| Mito_carr | 449..539 | CDD:278578 | 64/89 (72%) | ||
| Mito_carr | 544..633 | CDD:278578 | 73/88 (83%) | ||
| SLC25A12 | NP_003696.2 | N-terminal domain. /evidence=ECO:0000303|PubMed:25410934 | 2..294 | 134/297 (45%) | |
| EF-hand_7 | 16..80 | CDD:290234 | 34/63 (54%) | ||
| Linker loop domain. /evidence=ECO:0000303|PubMed:25410934 | 295..310 | 3/14 (21%) | |||
| Carrier domain. /evidence=ECO:0000303|PubMed:25410934 | 320..612 | 221/291 (76%) | |||
| Mito_carr | 327..420 | CDD:278578 | 74/92 (80%) | ||
| PTZ00169 | 330..603 | CDD:240302 | 209/272 (77%) | ||
| Mito_carr | 422..513 | CDD:278578 | 65/90 (72%) | ||
| Mito_carr | 514..609 | CDD:278578 | 76/94 (81%) | ||
| C-terminal domain. /evidence=ECO:0000303|PubMed:25410934 | 613..675 | 31/65 (48%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C165155521 | |
| Domainoid | 1 | 1.000 | 166 | 1.000 | Domainoid score | I3888 |
| eggNOG | 1 | 0.900 | - | - | E1_KOG0751 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 1 | 1.000 | - | - | H48235 | |
| Inparanoid | 1 | 1.050 | 767 | 1.000 | Inparanoid score | I543 |
| Isobase | 1 | 0.950 | - | 0.864974 | Normalized mean entropy | S1241 |
| OMA | 1 | 1.010 | - | - | QHG55987 | |
| OrthoDB | 1 | 1.010 | - | - | D1007928at2759 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0002875 | |
| OrthoInspector | 1 | 1.000 | - | - | otm42298 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_102019 | |
| Panther | 1 | 1.100 | - | - | O | PTHR45678 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R4126 |
| SonicParanoid | 1 | 1.000 | - | - | X1902 | |
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 1 | 0.960 | - | - | ||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 18 | 17.750 | |||||