Protein Alignment aralar1 and AGC1

DIOPT Version :10

• Sequence 1: NP_001247368.1
• Gene: aralar1 / 43616
• FlyBaseID: FBgn0028646
• Length: 707
• Species: Drosophila melanogaster
• Sequence 2: NP_015346.1
• Gene: AGC1 / 856132
• SGDID: S000006225
• Length: 902
• Species: Saccharomyces cerevisiae
• Alignment Length: 795
• Identity: 251/795 - (31%)
• Similarity: 349/795 - (43%)
• Gaps: 238/795 - (29%)

  Fly    32 TEKLREVFLKYASIQKNGEHYMTSEDFVRKFLGLFSE-----SAFNDESVRL----------LAN 81
            ||||            .||..:|.:||:.    |.|.     |.|.|.|..|          :..
Yeast    58 TEKL------------TGELILTYDDFIE----LISSSKTIYSKFTDHSFNLNQIPKNVFGCIFF 106

  Fly    82 IADTSKDGLISFSEFQAFEGLLCTPD----ALYRTAFQLFD------------------------ 118
            ..|....|.::.:::..|..||...:    .||. .|:.||
Yeast   107 AIDEQNKGYLTLNDWFYFNNLLEYDNYHLIILYE-FFRKFDVENLKAKQKKELGSSSFNLKAADD 170

  Fly   119 -----RKGNGTVSYAD-------FADVVQKTELHSKIPFSLDGPFIKRYFGDKKQRL----INYA 167
                 ..||..:|:.|       |.|.::.  ||.    |:|..|:|    |.|..|    ..:.
Yeast   171 RIKSINYGNRFLSFDDLLLNLNQFKDTIRL--LHE----SIDDNFVK----DNKLLLDWNDFRFL 225

  Fly   168 EFTQLLHDFHEEHAMEAF---------RSKDPAGTGFISPLDFQDIIVNVKRHLLTPGVRDNLVS 223
            :|.:..|:..|..::.:.         ..|...|...::.:|.|...:.:.::.||     .|:.
Yeast   226 KFYKCYHENEEYLSLNSLVTILQNDLKNEKIFIGFDRLAQMDSQGHRLALSKNQLT-----YLLR 285

  Fly   224 VTEGHKV---------------------SFPY--FIAFTSLLNNMELIKQVY-LHATEGS----- 259
            :...|:|                     |.||  |.....|..|.:|:.|:: .:.||.:
Yeast   286 LFYSHRVSADIFSSLNLSNTELLKADNNSIPYNVFKDIFYLFQNFDLLNQIFHKYVTENNLNEQD 350

  Fly   260 -RTDMITKDQIL--LAAQ-----TMSQITPLEIDILFHLAGAVHQAGWWKRR------------- 303
             |..::||:..:  |.||     .:.:.:|.:|::||.:.....:....::|
Yeast   351 IREQIVTKNDFMTVLNAQYNKVNNIIEFSPSQINLLFSIVANSKENRRLRKRNQDRDDELLNDHH 415

  Fly   304 --------------------RKIPPSSRIDYSDLSN----------------------------- 319
                                ||...|....|.|||:
Yeast   416 YDSDIDFFIHNEYLHGVSRSRKNLESFNDYYHDLSDGFDQDSGVKKASKASTGLFESVFGGKKDK 480

  Fly   320 --------------IAPEHYTKHMTHRLAEIKAVESPADRSAFIQ-----VLESSYRFTLGSFAG 365
                          |...:|...:.|::    .::...:.|.:|.     :.:|.|.|:|||.||
Yeast   481 ATMRSDLTIEDFMKILNPNYLNDLVHQM----ELQKNQNESLYINYYFYPIFDSLYNFSLGSIAG 541

  Fly   366 AVGATVVYPIDLVKTRMQNQRAGSYIGEVAYRNSWDCFKKVVRHEGFMGLYRGLLPQLMGVAPEK 430
            .:|||||||||.:|||||.||:     ...|:||.||..|::..||..|||.||.|||:||||||
Yeast   542 CIGATVVYPIDFIKTRMQAQRS-----LAQYKNSIDCLLKIISREGIKGLYSGLGPQLIGVAPEK 601

  Fly   431 AIKLTVNDLVRDKLTDKKGNIPTWAEVLAGGCAGASQVVFTNPLEIVKIRLQV----AGEIASGS 491
            ||||||||.:|::||||.|.:..:.|:::|..|||.||:||||||||||||||    .||....:
Yeast   602 AIKLTVNDFMRNRLTDKNGKLSLFPEIISGASAGACQVIFTNPLEIVKIRLQVQSDYVGENIQQA 666

  Fly   492 KIRAWSVVRELGLFGLYKGARACLLRDVPFSAIYFPTYAHTKAMM-----ADKDGYNHPLT--LL 549
            ...|..:|::|||.|||.|..|||:|||||||||||||||.|..:     .||...|...|  ||
Yeast   667 NETATQIVKKLGLRGLYNGVAACLMRDVPFSAIYFPTYAHLKKDLFDFDPNDKTKRNRLKTWELL 731

  Fly   550 AAGAIAGVPAASLVTPADVIKTRLQVVARSGQTTYTGVWDATKKIMAEEGPRAFWKGTAARVFRS 614
            .||||||:|||.|.||.||||||||:..|.|:|.|.|::.|.:.|:.||..|:|:||..|||.||
Yeast   732 TAGAIAGMPAAFLTTPFDVIKTRLQIDPRKGETKYNGIFHAIRTILKEESFRSFFKGGGARVLRS 796

  Fly   615 SPQFGVTLVTYELLQ 629
            |||||.||..|||.:
Yeast   797 SPQFGFTLAAYELFK 811

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aralar1	NP_001247368.1	FRQ1	32..178	CDD:444056	43/204 (21%)
		Mito_carr	350..448	CDD:395101	58/102 (57%)
		Mito_carr	449..539	CDD:395101	52/98 (53%)
		Mito_carr	544..633	CDD:395101	51/88 (58%)
AGC1	NP_015346.1	Mito_carr	531..619	CDD:395101	57/92 (62%)
		Mito_carr	620..713	CDD:395101	52/92 (57%)
		Mito_carr	723..814	CDD:395101	52/89 (58%)