DRSC/TRiP Functional Genomics Resources

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Protein Alignment aralar1 and SLC25A22

DIOPT Version :9

Sequence 1:NP_001247368.1 Gene:aralar1 / 43616 FlyBaseID:FBgn0028646 Length:707 Species:Drosophila melanogaster
Sequence 2:NP_001177989.1 Gene:SLC25A22 / 79751 HGNCID:19954 Length:323 Species:Homo sapiens


Alignment Length:298 Identity:121/298 - (40%)
Similarity:157/298 - (52%) Gaps:35/298 - (11%)


- Green bases have known domain annotations that are detailed below.


  Fly   361 GSFAGAVGATVVYPIDLVKTRMQNQRAGSYIGEVAYRNSWDCFKKVVRHEGFMGLYRGLLPQLMG 425
            |..||.:|.|.|:||||.|||:|||:.|..:    |.:..||..|.||.||:.|:|||....|..
Human    15 GGIAGLIGVTCVFPIDLAKTRLQNQQNGQRV----YTSMSDCLIKTVRSEGYFGMYRGAAVNLTL 75

  Fly   426 VAPEKAIKLTVNDLVRDKLTDKKGNIPTWAEVLAGGCAGASQVVFTNPLEIVKIRLQVAGEIASG 490
            |.|||||||..||..|.:|:.....:....|:|||..||..||:.|.|:|::||:||.||.||:.
Human    76 VTPEKAIKLAANDFFRHQLSKDGQKLTLLKEMLAGCGAGTCQVIVTTPMEMLKIQLQDAGRIAAQ 140

  Fly   491 SKIRA-----------------------------WSVVRELGLFGLYKGARACLLRDVPFSAIYF 526
            .||.|                             ..::|..|:.|||||..|.||||||||.:||
Human   141 RKILAAQGQLSAQGGAQPSVEAPAAPRPTATQLTRDLLRSRGIAGLYKGLGATLLRDVPFSVVYF 205

  Fly   527 PTYAHTKAMMADKDGYNHPLTL-LAAGAIAGVPAASLVTPADVIKTRLQVVARS-GQTTYTGVWD 589
            |.:|:...:.........|..: ..||.:||..||..|.|.||:|||||.:.|. .:.||:|:.|
Human   206 PLFANLNQLGRPASEEKSPFYVSFLAGCVAGSAAAVAVNPCDVVKTRLQSLQRGVNEDTYSGILD 270

  Fly   590 ATKKIMAEEGPRAFWKGTAARVFRSSPQFGVTLVTYEL 627
            ..:||:..|||.||.||...|....:|.||:..|.|.|
Human   271 CARKILRHEGPSAFLKGAYCRALVIAPLFGIAQVVYFL 308

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
aralar1NP_001247368.1 EF-hand_7 35..99 CDD:290234
EF-hand_8 51..99 CDD:290545
EF-hand_7 81..134 CDD:290234
EFh 84..135 CDD:298682
EF-hand_7 111..173 CDD:290234
Mito_carr 350..448 CDD:278578 42/86 (49%)
PTZ00169 358..631 CDD:240302 121/298 (41%)
Mito_carr 449..539 CDD:278578 42/118 (36%)
Mito_carr 544..633 CDD:278578 37/86 (43%)
SLC25A22NP_001177989.1 Mito_carr 4..98 CDD:278578 42/86 (49%)
Solcar 1 6..93 41/81 (51%)
Mito_carr 99..208 CDD:278578 41/108 (38%)
Solcar 2 101..214 42/112 (38%)
Mito_carr 221..306 CDD:278578 35/84 (42%)
Solcar 3 223..312 37/86 (43%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R4126
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.940

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