DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment aralar1 and colt

DIOPT Version :9

Sequence 1:	NP_001247368.1	Gene:	aralar1 / 43616	FlyBaseID:	FBgn0028646	Length:	707	Species:	Drosophila melanogaster
Sequence 2:	NP_477221.1	Gene:	colt / 33470	FlyBaseID:	FBgn0019830	Length:	306	Species:	Drosophila melanogaster

Alignment Length:	289	Identity:	82/289 - (28%)
Similarity:	138/289 - (47%)	Gaps:	18/289 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   358 FTLGSFAGAVGATVVYPIDLVKTRMQNQRAGSYIGEVAYRNSWDCFKKVVRHEGFMGLYRGLLPQ 422
            |..|.|.|.......:|:|.:|.|:|.....:...:..||.::||..|.:::||..|||:|:...
  Fly    19 FLTGGFGGICNVLSGHPLDTIKVRLQTMPRPAPGEQPLYRGTFDCAAKTIKNEGVRGLYKGMSAP 83

  Fly   423 LMGVAPEKAI---KLTVNDLVRDKLTDKKGNIPTWAEV-LAGGCAGASQVVFTNPLEIVKIRLQV 483
            |.||||..|:   ...:...::.:..|.|   .|:.:: :||..:|....:...|.|.:|:.||.
  Fly    84 LTGVAPIFAMCFAGYALGKRLQQRGEDAK---LTYPQIFVAGSFSGLFSTLIMAPGERIKVLLQT 145

  Fly   484 ----AGEIASGSKIR-AWSVVRELGLFGLYKGARACLLRDVPFSAIYFPTYAHTKAMMADKD--G 541
                .||......|. |..:.:|.||..::||:.|.:|||:|.:.:||..|...:.:...|.  |
  Fly   146 QQGQGGERKYNGMIDCAGKLYKEGGLRSVFKGSCATMLRDLPANGLYFLVYEALQDVAKSKSETG 210

  Fly   542 YNHPLTLLAAGAIAGVPAASLVTPADVIKTRLQVVARSGQTTYT-GVWDATKKIMAEEGPRAFWK 605
            .....:.:.||.:||:....|..||||:|:|||   .:.:.||. |:....|.::.::||.|.::
  Fly   211 QISTASTIFAGGVAGMAYWILGMPADVLKSRLQ---SAPEGTYKHGIRSVFKDLIVKDGPLALYR 272

  Fly   606 GTAARVFRSSPQFGVTLVTYELLQRLFYV 634
            |....:.|:.|.........||..:.|.:
  Fly   273 GVTPIMLRAFPANAACFFGIELANKFFNI 301

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
aralar1	NP_001247368.1	EF-hand_7	35..99	CDD:290234
		EF-hand_8	51..99	CDD:290545
		EF-hand_7	81..134	CDD:290234
		EFh	84..135	CDD:298682
		EF-hand_7	111..173	CDD:290234
		Mito_carr	350..448	CDD:278578	27/92 (29%)
		PTZ00169	358..631	CDD:240302	81/284 (29%)
		Mito_carr	449..539	CDD:278578	26/95 (27%)
		Mito_carr	544..633	CDD:278578	25/89 (28%)
colt	NP_477221.1	Mito_carr	12..107	CDD:395101	26/87 (30%)
		Mito_carr	112..202	CDD:395101	27/92 (29%)
		Mito_carr	210..299	CDD:395101	26/91 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45441734
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840