DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment aralar1 and CG1628

DIOPT Version :9

Sequence 1:	NP_001247368.1	Gene:	aralar1 / 43616	FlyBaseID:	FBgn0028646	Length:	707	Species:	Drosophila melanogaster
Sequence 2:	NP_572639.2	Gene:	CG1628 / 31990	FlyBaseID:	FBgn0030218	Length:	459	Species:	Drosophila melanogaster

Alignment Length:	319	Identity:	87/319 - (27%)
Similarity:	129/319 - (40%)	Gaps:	66/319 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   349 IQVLESSYRFTLGSFAGAVGATVVYPIDLVKTRMQNQRAGSYIGEVAYRNSWDCFKKVVRHEGFM 413
            |..:|....|..||..||....|..|:|.||.::|.       ...|||...|||....|.:|.:
  Fly   164 INFVEGLIDFLAGSLGGAAQVYVSQPLDTVKVKLQT-------FPEAYRGMLDCFLSTYRKDGVL 221

  Fly   414 -GLYRGLLPQLMGVAPEKAI-----------------KLTVNDLVRDKLTDKKGNIPTWAEVLAG 460
             |||.|.:|.:.....|.::                 |.|..||.                .:..
  Fly   222 RGLYAGSVPAVFANVAENSVLFAAYGGCQKFVAFCVGKETAGDLT----------------TVQN 270

  Fly   461 GCAGASQVVFTN----PLEIVKIRLQVAGEI------ASGSKIRA-WSVVREL----GLFGLYKG 510
            .|||:....|:.    |.|::|.:||...|:      |....||. |::.|.:    |:.|.|:|
  Fly   271 ACAGSLAACFSTLTLCPTELIKCKLQALREMKNFVEPAHPQDIRTPWTLTRYIWRTEGIRGFYRG 335

  Fly   511 ARACLLRDVPFSAIYFPTYAHTKAMM----ADKDGYNHPLTLLAAGAIAGVPAASLVTPADVIKT 571
            ..:..||::|....:|.:|..|:.::    ..||... ||..:.||||.||...:...||||||:
  Fly   336 LSSTFLREMPGYFFFFGSYEGTRELLRRDDQSKDDIG-PLRTMIAGAIGGVCLWTSTFPADVIKS 399

  Fly   572 RLQVVARSGQTTYTGVWDATKKIMAEEGPRAFWKGTAARVFRSSPQFGVTLVTYELLQR 630
            |:||     :.....::.....|:..||..|.::|....|.|:.|......|.||..:|
  Fly   400 RIQV-----KNLNESMFAVGADIVRREGVLALYRGLLPSVLRTIPATATLFVVYEYTKR 453

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
aralar1	NP_001247368.1	EF-hand_7	35..99	CDD:290234
		EF-hand_8	51..99	CDD:290545
		EF-hand_7	81..134	CDD:290234
		EFh	84..135	CDD:298682
		EF-hand_7	111..173	CDD:290234
		Mito_carr	350..448	CDD:278578	30/115 (26%)
		PTZ00169	358..631	CDD:240302	85/310 (27%)
		Mito_carr	449..539	CDD:278578	25/108 (23%)
		Mito_carr	544..633	CDD:278578	29/87 (33%)
CG1628	NP_572639.2	PTZ00169	162..455	CDD:240302	87/319 (27%)
		Mito_carr	170..252	CDD:278578	25/88 (28%)
		Mito_carr	263..364	CDD:278578	27/116 (23%)
		Mito_carr	369..455	CDD:278578	30/91 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45441852
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840