DRSC/TRiP Functional Genomics Resources

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Protein Alignment aralar1 and slc-25A18.1

DIOPT Version :9

Sequence 1:NP_001247368.1 Gene:aralar1 / 43616 FlyBaseID:FBgn0028646 Length:707 Species:Drosophila melanogaster
Sequence 2:NP_510493.2 Gene:slc-25A18.1 / 181596 WormBaseID:WBGene00008979 Length:313 Species:Caenorhabditis elegans


Alignment Length:283 Identity:109/283 - (38%)
Similarity:155/283 - (54%) Gaps:20/283 - (7%)


- Green bases have known domain annotations that are detailed below.


  Fly   361 GSFAGAVGATVVYPIDLVKTRMQNQRAGSYIGEVAYRNSWDCFKKVVRHEG------FMGLYRGL 419
            |..||.:|.:.|:||||||||:|||..|: .|::.|....||.|:..|..|      |.|:|.|.
 Worm    16 GGLAGIIGVSCVFPIDLVKTRLQNQTVGA-DGKLQYSGIADCAKQTWRSGGASTLAKFRGMYSGS 79

  Fly   420 LPQLMGVAPEKAIKLTVNDLVRDKLTDKKG--NIPTWAEVLAGGCAGASQVVFTNPLEIVKIRLQ 482
            ...::.:.|||||||..||..|.||. |:|  .:.....:||||.||..|:..|.|:|::||::|
 Worm    80 GVNILLITPEKAIKLVANDFFRHKLA-KEGEKQLSVGRGMLAGGLAGMFQISVTTPMELLKIQMQ 143

  Fly   483 VAGE-IASG-SKIRA----WSVVRELGLFGLYKGARACLLRDVPFSAIYFPTYAHTKAMMADK-D 540
            ..|. :..| .|:.|    ..:|:|.|:..||||..:.|.|||.||.||||.:|:..::...| |
 Worm   144 DQGRTLKPGQQKLSATQLTMKLVKENGIAALYKGLSSTLARDVTFSVIYFPLFAYLDSLAPRKPD 208

  Fly   541 GYNHPLTL--LAAGAIAGVPAASLVTPADVIKTRLQVVAR-SGQTTYTGVWDATKKIMAEEGPRA 602
            |....:..  ..||..:|..::..|||.||||||:|.:.: :.:..|..:.||...|...|||:|
 Worm   209 GSGDAVFYGSFLAGLTSGAASSFCVTPLDVIKTRMQTINKGANEIVYKNIPDAFVTIFKNEGPKA 273

  Fly   603 FWKGTAARVFRSSPQFGVTLVTY 625
            .:||.|.|:...:|.||:....|
 Worm   274 LFKGAACRMMVMAPLFGIAQTVY 296

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
aralar1NP_001247368.1 EF-hand_7 35..99 CDD:290234
EF-hand_8 51..99 CDD:290545
EF-hand_7 81..134 CDD:290234
EFh 84..135 CDD:298682
EF-hand_7 111..173 CDD:290234
Mito_carr 350..448 CDD:278578 40/92 (43%)
PTZ00169 358..631 CDD:240302 109/283 (39%)
Mito_carr 449..539 CDD:278578 36/97 (37%)
Mito_carr 544..633 CDD:278578 29/85 (34%)
slc-25A18.1NP_510493.2 PTZ00169 3..278 CDD:240302 102/263 (39%)
Mito_carr 5..108 CDD:278578 41/93 (44%)
Mito_carr 110..199 CDD:278578 35/88 (40%)
Mito_carr 215..296 CDD:278578 28/80 (35%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R4126
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.940

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