DRSC/TRiP Functional Genomics Resources

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Protein Alignment aralar1 and slc-25A18.2

DIOPT Version :9

Sequence 1:NP_001247368.1 Gene:aralar1 / 43616 FlyBaseID:FBgn0028646 Length:707 Species:Drosophila melanogaster
Sequence 2:NP_501198.1 Gene:slc-25A18.2 / 177518 WormBaseID:WBGene00018901 Length:309 Species:Caenorhabditis elegans


Alignment Length:285 Identity:103/285 - (36%)
Similarity:153/285 - (53%) Gaps:28/285 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly   361 GSFAGAVGATVVYPIDLVKTRMQNQRAGSYIGEVAYRNSWDCFKK------VVRHEGFMGLYRGL 419
            |..:|.||.:.|:|:||||||:|||:     |...|....|||||      ..|.....|:|:|.
 Worm    27 GGISGIVGVSCVFPMDLVKTRLQNQK-----GTSKYTGIADCFKKSWQAGAPGRLNQIKGMYQGA 86

  Fly   420 LPQLMGVAPEKAIKLTVNDLVRDKL-TDKKGNIPTWAEVLAGGCAGASQVVFTNPLEIVKIRLQV 483
            ...:..:.|||||||..||..|..| .|....:.|...::||..||..|||.|.|:|::|||:|.
 Worm    87 SVNIFLITPEKAIKLVANDFFRHALMKDHDERLSTPRGMIAGASAGFCQVVITTPMELLKIRMQQ 151

  Fly   484 AGEIASGSKIRAWSVV-RELGLFGLYKGARACLLRDVPFSAIYFPTYAHTKAM---MADKDGYNH 544
            :.:....:|: .|::: ::.|:..||||....:.|||.|||:|||.:|:...:   ..|..|...
 Worm   152 SSDKVKATKL-IWNLLTKDGGVRALYKGLGPTMARDVSFSAMYFPLFAYLDGLGPRKKDDSGDAV 215

  Fly   545 PLTLLAAGAIAGVPAASLVTPADVIKTRLQVVARSGQTTYTGVWDATKKIMAEEGPRAFWKGTAA 609
            ......:|..||..|:..|||.||:|||:|    :|.:.|.|::.|..:|:|:||.:|.:||...
 Worm   216 FWASFVSGLTAGATASLSVTPLDVVKTRIQ----TGGSNYNGIFHAFYRILADEGVKALFKGAIC 276

  Fly   610 RVFRSSPQFGVTLVTYELLQRLFYV 634
            |:...:|.||:.       |.::||
 Worm   277 RMMVMAPLFGIA-------QTVYYV 294

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
aralar1NP_001247368.1 EF-hand_7 35..99 CDD:290234
EF-hand_8 51..99 CDD:290545
EF-hand_7 81..134 CDD:290234
EFh 84..135 CDD:298682
EF-hand_7 111..173 CDD:290234
Mito_carr 350..448 CDD:278578 38/93 (41%)
PTZ00169 358..631 CDD:240302 101/280 (36%)
Mito_carr 449..539 CDD:278578 32/93 (34%)
Mito_carr 544..633 CDD:278578 29/88 (33%)
slc-25A18.2NP_501198.1 Mito_carr 17..114 CDD:278578 37/91 (41%)
PTZ00168 18..277 CDD:185494 96/259 (37%)
Mito_carr 117..200 CDD:278578 32/83 (39%)
Mito_carr 216..292 CDD:278578 29/86 (34%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R4126
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.940

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