Protein Alignment aralar1 and K02F3.2

DIOPT Version :10

• Sequence 1: NP_001247368.1
• Gene: aralar1 / 43616
• FlyBaseID: FBgn0028646
• Length: 707
• Species: Drosophila melanogaster
• Sequence 2: NP_001263698.1
• Gene: K02F3.2 / 175242
• WormBaseID: WBGene00019326
• Length: 716
• Species: Caenorhabditis elegans
• Alignment Length: 695
• Identity: 386/695 - (55%)
• Similarity: 479/695 - (68%)
• Gaps: 38/695 - (5%)

  Fly    18 ARCQESPSL----LKRAGTEKLREVFLKYASIQKNGEHYMTSEDFVRKFLGLFSESAFNDESVRL 78
            |.|....::    :.||..:.||.:|.::|:.:..|:..||.|||:|.:|||::|..:|.|:|||
 Worm    36 AECNAETAISQRSIPRANPDHLRPIFDRFATKEIKGKKLMTPEDFIRGYLGLYTEENYNKETVRL 100

  Fly    79 LANIADTSKDGLISFSEFQAFEGLLCTPDALYRTAFQLFDRKGNGTVSYADFADVVQKTE-LHSK 142
            ||:.|||:|||.|||.||.|||.|||:|||||.|||:||||..:.|:|..:|..|::.|: ||.:
 Worm   101 LASAADTTKDGDISFEEFCAFEALLCSPDALYLTAFELFDRNASDTISCDEFEAVIRHTQPLHDQ 165

  Fly   143 IPFSLDGPFIKRYFGDKKQRLINYAEFTQLLHDFHEEHAMEAFRSKDPAGTGFISPLDFQDIIVN 207
             .|.....|||||||..|||.:||..|.||||||:||..::||:..|..|.|.||.||||.|:..
 Worm   166 -DFDFSSEFIKRYFGADKQRNVNYHSFCQLLHDFYEEQGIQAFKRYDKNGNGTISSLDFQQIMTT 229

  Fly   208 VKRHLLTPGVRDNLVSVT----EGHK--------VSFPYFIAFTSLLNNMELIKQVYLHATEGSR 260
            ||.||||..||.||::|:    .|||        |:|||:.||.|||..|||||:||:..|.|:.
 Worm   230 VKGHLLTDFVRHNLIAVSGGGASGHKFSDTRGGFVTFPYYAAFNSLLAKMELIKRVYVSTTRGNL 294

  Fly   261 TDMITKDQILLAAQTMSQITPLEIDILFHLAGAVHQAGWWKRRRKIPPSSRIDYSDLSNIAPEHY 325
            ...:||::.|.|.|:.:|:||.|::|||||:...|           |....:...|:..|.||..
 Worm   295 DIEMTKEEFLHAIQSYTQVTPYEVEILFHLSELNH-----------PGRKTLCLKDIQAIDPERL 348

  Fly   326 TK-HMTHRLAEIKAVESPADRSAFIQVLESSYRFTLGSFAGAVGATVVYPIDLVKTRMQNQR-AG 388
            .: ....||..||||....||......|||:|||.|||.|||.|||.||||||||||||||| :|
 Worm   349 KRVSQMDRLINIKAVHHKDDRGVGTAFLESAYRFLLGSVAGACGATAVYPIDLVKTRMQNQRTSG 413

  Fly   389 SYIGEVAYRNSWDCFKKVVRHEGFMGLYRGLLPQLMGVAPEKAIKLTVNDLVRDKLTDKKGNIPT 453
            |::|||.|:||.|||||||:.||.:|||||||||::|||||||||||:||.:|||.| |.|.||.
 Worm   414 SFVGEVMYKNSLDCFKKVVKFEGLLGLYRGLLPQIVGVAPEKAIKLTMNDYMRDKFT-KDGKIPL 477

  Fly   454 WAEVLAGGCAGASQVVFTNPLEIVKIRLQVAGEI-ASGSKIRAWSVVRELGLFGLYKGARACLLR 517
            :.|::|||..|..||||||||||||||||.|||: .:|.||..::|::|||..|||||:|||.||
 Worm   478 YGEIIAGGTGGMCQVVFTNPLEIVKIRLQTAGEVQQAGKKIGVFTVLKELGFLGLYKGSRACFLR 542

  Fly   518 DVPFSAIYFPTYAHTKAMMADKDGYNHPLTLLAAGAIAGVPAASLVTPADVIKTRLQVVARSGQT 582
            |:||||||||.|||.|...||:||.|.|.||.|:..|||||||.||||||||||||||.||:|||
 Worm   543 DIPFSAIYFPAYAHAKLASADEDGMNSPGTLFASAFIAGVPAAGLVTPADVIKTRLQVAARAGQT 607

  Fly   583 TYTGVWDATKKIMAEEGPRAFWKGTAARVFRSSPQFGVTLVTYELLQRLFYVDFGGTQPKGSEAH 647
            ||.||.|..:|::.||||.:.||||||||.||||||.|||:|||:|||||||||.|::|.|||.
 Worm   608 TYNGVIDCARKLIKEEGPMSLWKGTAARVCRSSPQFAVTLLTYEVLQRLFYVDFAGSRPTGSEL- 671

  Fly   648 KITTPLEQAAASVTTENVDHIGGYRAAVPLLAGVESKFGLYLPRF 692
             .||...|..:|.   |.||:|||:.|....:|:|.||||:||:|
 Worm   672 -ATTKTIQDESST---NPDHVGGYKLAAATFSGIEHKFGLFLPKF 712

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aralar1	NP_001247368.1	FRQ1	32..178	CDD:444056	78/146 (53%)
		Mito_carr	350..448	CDD:395101	73/98 (74%)
		Mito_carr	449..539	CDD:395101	58/90 (64%)
		Mito_carr	544..633	CDD:395101	64/88 (73%)
K02F3.2	NP_001263698.1	FRQ1	55..228	CDD:444056	92/173 (53%)
		EFh_PEF	136..>266	CDD:355382	61/130 (47%)
		EF-hand motif	136..164	CDD:320054	11/27 (41%)
		EF-hand motif	173..201	CDD:320054	19/27 (70%)
		EF-hand motif	202..231	CDD:320054	12/28 (43%)
		PTZ00169	382..656	CDD:240302	193/274 (70%)
		Mito_carr	569..658	CDD:395101	64/88 (73%)