DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG15537 and crhbp

DIOPT Version :9

Sequence 1:	NP_001097981.1	Gene:	CG15537 / 43614	FlyBaseID:	FBgn0039770	Length:	353	Species:	Drosophila melanogaster
Sequence 2:	NP_001003459.1	Gene:	crhbp / 445065	ZFINID:	ZDB-GENE-040801-196	Length:	321	Species:	Danio rerio

Alignment Length:	238	Identity:	73/238 - (30%)
Similarity:	115/238 - (48%)	Gaps:	25/238 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   109 QPEV-CGLYVIGEPDTIVEITMKHYDANCETGALMAFVDGWELNGEYFPGIKDHHRPLEERVYEF 172
            :|:: |.::.||||..::.|.....:.:|..|..:...|||.:.||.||..:||..||.||..::
Zfish    78 RPQLNCAVFFIGEPTDVISIEYDSVNIDCRGGDFIKVFDGWVMKGEKFPSSQDHPLPLYERYTDY 142

  Fly   173 CNNYRQWPRVSNKKFFRSSQNAALLQYRIPVRGSFVANVRFHKITQ--PCNVLVQDTAAMYKMTN 235
            |......|.|      |||||.|:|.:|:...||.. .|.|.|:..  ||||:.|.....:.|..
Zfish   143 CETGVSRPIV------RSSQNVAMLFFRLHQSGSSF-TVTFRKLINPFPCNVVSQTPEGSFTMII 200

  Fly   236 FGQARNCTISALFPAVVSLASLRIG-----GKSVRAQPKVNYDCQLPSDRLEIGGAAGLDAIGME 295
            ..|.|||:.|.::|..:.:..|.:|     .:|:       ..|....|.:|:.|..|:|...|.
Zfish   201 PQQHRNCSFSIIYPVEIQIGELSLGQHNDLKRSI-------LGCAGSGDFVELLGGNGMDTSKMF 258

  Fly   296 QASAVCGASSDLGPEQ-AIFCGVSTVRLVSSGRYQNQAAIVLR 337
            ..:.:|.:.:  ||.| .:.|..:.||:||||::.|:.:...|
Zfish   259 PMADLCYSFN--GPAQMKVGCDNTVVRMVSSGKFVNRVSFQYR 299

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15537	NP_001097981.1	CRF-BP	<109..345	CDD:283162	73/238 (31%)
crhbp	NP_001003459.1	CRF-BP	1..307	CDD:283162	73/238 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170590714
Domainoid	1	1.000	108	1.000	Domainoid score	I6425
eggNOG	1	0.900	-	-		E1_28J9S
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1418
Inparanoid	1	1.050	107	1.000	Inparanoid score	I4896
OMA	1	1.010	-	-		QHG47583
OrthoDB	1	1.010	-	-		D1361570at2759
OrthoFinder	1	1.000	-	-		FOG0008255
OrthoInspector	1	1.000	-	-		oto38725
orthoMCL	1	0.900	-	-		OOG6_109275
Panther	1	1.100	-	-	LDO	PTHR10278
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5320
SonicParanoid	1	1.000	-	-		X6223
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800