Protein Alignment CG15537 and CRHBP

DIOPT Version :10

• Sequence 1: NP_001097981.1
• Gene: CG15537 / 43614
• FlyBaseID: FBgn0039770
• Length: 353
• Species: Drosophila melanogaster
• Sequence 2: NP_001873.2
• Gene: CRHBP / 1393
• HGNCID: 2356
• Length: 322
• Species: Homo sapiens
• Alignment Length: 248
• Identity: 74/248 - (29%)
• Similarity: 121/248 - (48%)
• Gaps: 19/248 - (7%)

  Fly   103 ADVQELQPEVCGLYVIGEPDTIVEITMKHYD---ANCETGALMAFVDGWELNGEYFPGIKDHHRP 164
            ||..:|.   |..:.|.||:..:.|   |||   .:|:.|..:...|||.|.||.||..:||..|
Human    74 ADRPQLH---CAAFFISEPEEFITI---HYDQVSIDCQGGDFLKVFDGWILKGEKFPSSQDHPLP 132

  Fly   165 LEERVYEFCNNYRQWPRVSNKKFFRSSQNAALLQYRIPVRGS-FVANVRFHKITQPCNVLVQDTA 228
            ..||..:||.:      ..:::..|||||.|::.:|:...|: |...::......||||:.|...
Human   133 SAERYIDFCES------GLSRRSIRSSQNVAMIFFRVHEPGNGFTLTIKTDPNLFPCNVISQTPN 191

  Fly   229 AMYKMTNFGQARNCTISALFPAVVSLASLRIGGKSVRAQPKVNYDCQLPSDRLEIGGAAGLDAIG 293
            ..:.:....|.|||:.|.::|.|:.::.|.:|..:.....|.:..|:...|.:|:.|..|||...
Human   192 GKFTLVVPHQHRNCSFSIIYPVVIKISDLTLGHVNGLQLKKSSAGCEGIGDFVELLGGTGLDPSK 256

  Fly   294 MEQASAVCGASSDLGPEQ-AIFCGVSTVRLVSSGRYQNQAAIVLRKADVPDME 345
            |...:.:|....  ||.| .:.|..:.||:||||::.|:.....|:.:..::|
Human   257 MTPLADLCYPFH--GPAQMKVGCDNTVVRMVSSGKHVNRVTFEYRQLEPYELE 307

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15537	NP_001097981.1	CRF-BP	<109..345	CDD:461650	70/240 (29%)
CRHBP	NP_001873.2	CRF-BP	10..307	CDD:461650	73/246 (30%)