DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15537 and Crhbp

DIOPT Version :9

Sequence 1:	NP_001097981.1	Gene:	CG15537 / 43614	FlyBaseID:	FBgn0039770	Length:	353	Species:	Drosophila melanogaster
Sequence 2:	NP_940800.1	Gene:	Crhbp / 12919	MGIID:	88497	Length:	322	Species:	Mus musculus

Alignment Length:	251	Identity:	75/251 - (29%)
Similarity:	121/251 - (48%)	Gaps:	19/251 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   103 ADVQELQPEVCGLYVIGEPDTIVEITMKHYD---ANCETGALMAFVDGWELNGEYFPGIKDHHRP 164
            ||..:|.   |..:.||||:..:.|   |||   .:|:.|..:...|||.|.||.||..:||..|
Mouse    74 ADRPQLH---CAAFFIGEPEEFITI---HYDLVSIDCQGGDFLKVFDGWILKGEKFPSSQDHPLP 132

  Fly   165 LEERVYEFCNNYRQWPRVSNKKFFRSSQNAALLQYRIPVRGS-FVANVRFHKITQPCNVLVQDTA 228
            ..:|..:||.:      ...::..|||||.|::.:|:...|: |...::......||||:.|..:
Mouse   133 TMKRYTDFCES------GLTRRSIRSSQNVAMVFFRVHEPGNGFTITIKTDPNLFPCNVISQTPS 191

  Fly   229 AMYKMTNFGQARNCTISALFPAVVSLASLRIGGKSVRAQPKVNYDCQLPSDRLEIGGAAGLDAIG 293
            ..:.:....|.:||:.|.::|..:.::.|.:|........|....|....|.:|:.|..|||...
Mouse   192 GRFTLVVPYQHQNCSFSIIYPVAIKISDLTLGHLHGLQLKKPAAGCGGTGDFVELLGGTGLDPSK 256

  Fly   294 MEQASAVCGASSDLGPEQ-AIFCGVSTVRLVSSGRYQNQAAIVLRKADVPDMEIAT 348
            |...:.:|  ...|||.| .|.|..:.||:||||::.|:.....|:.:..::|.:|
Mouse   257 MMPLADLC--YPFLGPAQMKISCDNAVVRMVSSGKHINRVTFEYRQLEPFELETST 310

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15537	NP_001097981.1	CRF-BP	<109..345	CDD:283162	70/240 (29%)
Crhbp	NP_940800.1	CRF-BP	1..307	CDD:283162	73/246 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846002
Domainoid	1	1.000	106	1.000	Domainoid score	I6624
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1418
Inparanoid	1	1.050	109	1.000	Inparanoid score	I4893
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG47583
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0008255
OrthoInspector	1	1.000	-	-		oto93748
orthoMCL	1	0.900	-	-		OOG6_109275
Panther	1	1.100	-	-	LDO	PTHR10278
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5320
SonicParanoid	1	1.000	-	-		X6223
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	14	13.930