DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15534 and smpdl3b

DIOPT Version :9

Sequence 1:	NP_651792.1	Gene:	CG15534 / 43613	FlyBaseID:	FBgn0039769	Length:	666	Species:	Drosophila melanogaster
Sequence 2:	NP_001315485.1	Gene:	smpdl3b / 564392	ZFINID:	ZDB-GENE-041008-132	Length:	457	Species:	Danio rerio

Alignment Length:	486	Identity:	129/486 - (26%)
Similarity:	212/486 - (43%)	Gaps:	103/486 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   217 HLTDIHYDPEYAEGSNAACDEPMCCRNSLPEGSDSSAAAGFWSDYRDCDCPKRLILSAFEHIKEN 281
            |::|:|:||.|...|::...    |.:|   |...:..||.:.|| .||.|..||.|:...::|
Zfish    28 HISDLHWDPSYDLSSSSQSK----CASS---GGRPTPHAGRYGDY-VCDSPWSLINSSLTAMRE- 83

  Fly   282 HKI----EWIYHTGDVPPHNVWSTT-RQGNLDMLSEIDELLAKYFPDTPIYPCLGNHEPHPANVF 341
              |    ::|..|||..||...... .|..|.::..:..::...||.|.:|..:|||:.||.|
Zfish    84 --ILPDPDFIMWTGDDTPHVPDDQLGEQAVLRIIGNLTNIIKSTFPKTKVYSAMGNHDYHPKN-- 144

  Fly   342 GNDEIPSSLRVDWLYEHVWSLWSKWLPAEAEETVLRGGYYTAS--PSKGHRIVALNSMDCYLYNW 404
               ::|.:...  :||...:||..||...::||...|||||..  ...|.|::.||:.
Zfish   145 ---QMPPAKST--IYEQTANLWRDWLHTASQETFKTGGYYTEKLLNQTGLRVIVLNTN------- 197

  Fly   405 WLFYNATLIQE-------QLQWFHDTLLSAEEAGESVHILTHIPAG-------DGDCWCNWSQEY 455
             |:|:...:.|       |..|....|..|.:..|.|:::.|:|.|       .|  |  :.:|:
Zfish   198 -LYYDQNKLTEKVKDPADQFSWADKVLQDAAKNNEKVYLIGHVPPGLFEKKRDKG--W--FRKEF 257

  Fly   456 NR----VLTRFNGIITGVFSGHTHKDEMNLHYSEDG------YAT--VVNW--------NGGSLT 500
            |:    ::.:.:.:|.|.|.||.|.|...:.|:..|      |.|  |..|        :||:
Zfish   258 NKRYIELIQKHSAVIMGQFFGHHHTDSFRMFYNSKGSPISAMYLTPGVTPWITTLPGVIDGGN-- 320

  Fly   501 SYSNKNPNYRLYELHPENWQVLDHHTYTFNLTEANLTPDEQPKWELEYQFTKEY-TEDTSPAGID 564
                 ||..|::|...:...|.|..||..|||.||:.   :.:||.||:.|:.: ..|.|||.:.
Zfish   321 -----NPGIRIFEYDTKTLLVKDIITYYLNLTYANIA---RARWEKEYRLTEAFRVPDASPASMH 377

  Fly   565 RLLLEMAEKPDLLRKFWRNKFTNSDPKLAEGCDNACLSKTICRIATSNYQERTRCKELQAILAES 629
            |::..::.:...|:|::.....:.|  |:| |...|....:|.:...:|....:|     :|.|
Zfish   378 RVMERISSEKCSLQKYFELNSVSYD--LSE-CHADCRVDHVCALREVDYDAYEKC-----VLKE- 433

  Fly   630 LENEPDTDDNNGGGAAGLSALSLASLLALLA 660
                        ||::....|.:..|..:|:
Zfish   434 ------------GGSSNAPVLFILFLSLMLS 452

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15534	NP_651792.1	MPP_ASMase	215..510	CDD:277321	91/333 (27%)
CG15534	NP_651792.1	Metallophos	271..477	CDD:278574	62/230 (27%)
smpdl3b	NP_001315485.1	MPP_ASMase	26..325	CDD:277321	91/333 (27%)
smpdl3b	NP_001315485.1	Metallophos	26..283	CDD:278574	80/284 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3770
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53732
OrthoDB	1	1.010	-	-		D369165at33208
OrthoFinder	1	1.000	-	-		FOG0000551
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.830