Protein Alignment CG15534 and asm-2

DIOPT Version :10

• Sequence 1: NP_651792.1
• Gene: CG15534 / 43613
• FlyBaseID: FBgn0039769
• Length: 666
• Species: Drosophila melanogaster
• Sequence 2: NP_509894.2
• Gene: asm-2 / 181323
• WormBaseID: WBGene00000212
• Length: 618
• Species: Caenorhabditis elegans
• Alignment Length: 667
• Identity: 180/667 - (26%)
• Similarity: 278/667 - (41%)
• Gaps: 110/667 - (16%)

  Fly     9 LLGIGILFVGCGAFSLPSVYDVLSKDQQATSFVSASIAEEISREYLKY-----HRTGIETERLRQ 68
            :|||||               ||:......|.|.....:|  .||.|:     :...:...:.:.
 Worm     7 ILGIGI---------------VLALVSNVESGVLRKPVDE--HEYEKWTNARGNEAAVPPPKYKM 54

  Fly    69 LGKDIRSSHSKKAIFTESMADLTSTDQFFVCTLCRSTINVFARTFTEGELSGPERDDEAKKLMLG 133
            |      .::||||.......::       |..|     .||....:..::....|:|....::.
 Worm    55 L------RYAKKAINEPENRKMS-------CLFC-----TFAVDGVQALIAQNSTDNEIAAFLVN 101

  Fly   134 MCDYFAISTQEVCSGLFDLNWPILDFILNETVAKSNTFCSMLPIPICQVKQDEYNLT----LSIQ 194
            :||.|.:....||..:.......:.|:|..:|......|...   |......:..||    ::|.
 Worm   102 LCDLFDVEQPHVCKNIIYAFKDEVVFVLERSVFTPEEICGAF---IANCGHSDKPLTHMWNITIP 163

  Fly   195 GDLPQESNSNLPAK-------TSEDILVLHLTDIHYDPEYAEGSNAACD-------EPMCCRNSL 245
            |..|       |.|       ......||||:|||.|.:|..|:.|.|.       ..||||:
 Worm   164 GGKP-------PIKPWPKIPDNKPTFKVLHLSDIHIDHQYVVGTEAYCQLDSALGTYAMCCRD-- 219

  Fly   246 PEGSDSSAA------------AGFWSDYRDCDCPKRLILSAFEHIKENHK-IEWIYHTGDVPPHN 297
             ...||..|            ||.|.....||.|.:...||.:||.:..| :::|..|||...|:
 Worm   220 -YSQDSQGAPTNLKDKPIYVPAGPWGMPYLCDLPYQTFESAMKHISKTFKDLDYIIITGDFEAHD 283

  Fly   298 VWSTTRQGNLDMLSEIDELLAKYFPDTPIYPCLGNHEPHPANVFGNDEIP--SSLRVDWLYEHVW 360
            .|..|.....:.::.:..:..:|||..|:|..:||||..|.:......:|  .:....|||:.:.
 Worm   284 SWDYTEDLTRENMNNMTNVFLEYFPGVPVYVSIGNHEGVPQDAMAPHTMPEYDTRGPQWLYKIMS 348

  Fly   361 SLWSKWLPAEAEETVLRGGYYTASPSKGHRIVALNSMDCYLYNWWLFYNATLIQEQLQWFHDTLL 425
            .:||.|:|.||.:||.....|...|..|.::::||::.|..:|::|:.|.......|:|..:.|.
 Worm   349 EMWSHWIPQEALDTVQYRASYAVYPKPGLKLISLNTIYCSEFNFYLYVNEVDPDATLEWLIEELQ 413

  Fly   426 SAEEAGESVHILTHIPAGDGDCWCNWSQEYNRVLTRFNGIITGVFSGHTHKDEMNLHYSEDG--- 487
            .:|..||.|||::|||.||..|...||..:..::.|:...|..:|.||||.|:..::|..|.
 Worm   414 DSENKGELVHIISHIPPGDNYCLKGWSWNFFEIVKRYENTIAQMFYGHTHYDQFMVYYDMDDPNR 478

  Fly   488 YATVVNWNGGSLTSYSNKNPNYRLYEL----HPENWQVLDHHTYTFNLTEANLTPDEQPKWELEY 548
            .....||...|||:|...||.||:||:    ....:.|.|..||..|:||||: .:::|:|.|.|
 Worm   479 RPFHFNWISPSLTTYDWLNPAYRIYEIDGGYEGATYTVKDAKTYFANVTEANM-KNKEPEWVLSY 542

  Fly   549 QFTKEYTE--DTSPAG----IDRLLLEMAEKPDLLRKFWRNKFTNSDPKLAEGC--DNACLSKTI 605
            . |:|:.:  |.||..    .|:|........|.:|.::||.:.|.       |  |..|....:
 Worm   543 D-TREHYQMADFSPQSWSDLSDKLWTNTTLFRDYVRLYYRNHYNNE-------CYTDYKCRYTFV 599

  Fly   606 CRIATSNYQERTRCKEL 622
            |.|......:.:.|..|
 Worm   600 CDIKKGRSYDESFCDHL 616

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15534	NP_651792.1	MPP_ASMase	215..510	CDD:277321	103/319 (32%)
		ASMase_C	502..619	CDD:466022	37/128 (29%)
asm-2	NP_509894.2	SapB	70..143	CDD:214797	15/84 (18%)
		MPP_ASMase	184..501	CDD:277321	103/319 (32%)
		ASMase_C	497..602	CDD:466022	35/113 (31%)