Protein Alignment CG2218 and UBE4B

DIOPT Version :9

• Sequence 1: NP_001287613.1
• Gene: CG2218 / 43611
• FlyBaseID: FBgn0039767
• Length: 486
• Species: Drosophila melanogaster
• Sequence 2: XP_005263479.1
• Gene: UBE4B / 10277
• HGNCID: 12500
• Length: 1353
• Species: Homo sapiens
• Alignment Length: 404
• Identity: 86/404 - (21%)
• Similarity: 138/404 - (34%)
• Gaps: 143/404 - (35%)

  Fly    21 VCEDGYTA-ANLVADDVEQLERGFMCFAVCKPPIEIVFDFPKAVDMKVIKLWPS----------C 74
            :|...|.. ..|||..||.:   ||.....:|..:..|:..:...:....|.||          .
Human   970 LCNQNYIRNPYLVAKLVEVM---FMTNPAVQPRTQKFFEMIENHPLSTKLLVPSLMKFYTDVEHT 1031

  Fly    75 GALR------------STAFELHGRHDGIWERVA--------------FVRDLGRGVDSVTFCY- 112
            ||..            ||.|:      .:|:.:|              |||.:...::..||..
Human  1032 GATSEFYDKFTIRYHISTIFK------SLWQNIAHHGTFMEEFNSGKQFVRYINMLINDTTFLLD 1090

  Fly   113 --------------------QSDYNSRSSSNSEQSEKVFFFKSAHKILA-STNSVKVVIRATERC 156
                                |.|...|....:.||:.....:.:...|| :|.:|.:....|::.
Human  1091 ESLESLKRIHEVQEEMKNKEQWDQLPRDQQQARQSQLAQDERVSRSYLALATETVDMFHILTKQV 1155

  Fly   157 -PPVLRK--------------VQMWGLPARSLDKADRELV----KTIWSEISDPYGQRDAAQ--- 199
             .|.||.              .|:.|...|.|...:.|..    |.:..:::|.|.|.|.|:
Human  1156 QKPFLRPELGPRLAAMLNFNLQQLCGPKCRDLKVENPEKYGFEPKKLLDQLTDIYLQLDCARFAK 1220

  Fly   200 -TPTGQRSPPRN-----VPELRD---QSTLSI---------------------------PEEFLD 228
             ....|||..:.     :.::|.   :||::|                           |:||.|
Human  1221 AIADDQRSYSKELFEEVISKMRKAGIKSTIAIEKFKLLAEKVEEIVAKNARAEIDYSDAPDEFRD 1285

  Fly   229 SITWELMIFPTVLPSGKVVDQSTIDKHAEEEAKWGRQPSDPFTGLEFNAQ--RKAILHLA--LKA 289
            .:...||..|..||||.::|:|.|.:|..      ..|:||     ||.|  .:::|...  ||.
Human  1286 PLMDTLMTDPVRLPSGTIMDRSIILRHLL------NSPTDP-----FNRQTLTESMLEPVPELKE 1339

  Fly   290 RIEKFLME--NSEH 301
            :|:.::.|  ||:|
Human  1340 QIQAWMREKQNSDH 1353

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2218	NP_001287613.1	U-box	222..300	CDD:252675	28/110 (25%)
UBE4B	XP_005263479.1	Ufd2P_core	642..1262	CDD:287392	57/300 (19%)
		U-box	1279..1350	CDD:252675	26/81 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5113
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900