Protein Alignment heca and Heca

DIOPT Version :10

• Sequence 1: NP_788768.1
• Gene: heca / 43604
• FlyBaseID: FBgn0010113
• Length: 1080
• Species: Drosophila melanogaster
• Sequence 2: NP_001028604.1
• Gene: Heca / 380629
• MGIID: 2685715
• Length: 544
• Species: Mus musculus
• Alignment Length: 678
• Identity: 186/678 - (27%)
• Similarity: 267/678 - (39%)
• Gaps: 198/678 - (29%)

  Fly     4 RRNSNISSSGNSTQQQHQQQLQQQHQTQQHQLLQFYAENVNSSGVLMAPMQ----------GTGG 58
            |:|...:|||:            :.:.....|....|....:.|.|.|...          ||||
Mouse    11 RKNKRANSSGD------------EQENGAGALAAAGATGAAAGGALAAAAAGCGAASPGAVGTGG 63

  Fly    59 VGGVGGGG-------MVHCCLPSGDC---------------RKLDTLIHLNELSLADCIRVLCNN 101
            ..|.||.|       :......:||.               |.:|       |...|..:|:|||
Mouse    64 AAGPGGAGTGAANATVAAGAAAAGDAKNGAPCATPLICSFGRPVD-------LEKDDYQKVVCNN 121

  Fly   102 ENCSAGQYMHRECFEWWEASVLQALKANGRARSWSERQRLQHLWTKKGYELVQKACSCKCGRGQL 166
            |:|....:||.:||..||:|:|......||||||:|:|..|::||||||:|..:.|||:||:|.|
Mouse   122 EHCPCSTWMHLQCFYEWESSILVQFNCIGRARSWNEKQCRQNMWTKKGYDLAFRFCSCRCGQGHL 186

  Fly   167 RKDLDWVPPSSQGVIYLNGSGNRPTLANGSLSEDDDKKKAKKKRNRNNNNNNGGGGGGGAGVNGN 231
            :||.||......                    :|:.|||                    :|...|
Mouse   187 KKDTDWYQVKRM--------------------QDEKKKK--------------------SGSEKN 211

  Fly   232 TKTPLSNNNGNSYAGLTPN-PNVGVIGSGLPHNNGNTASNGSSGNNGSSGVLQTSALATFSNILN 295
            |..|.......:..|...| |..| :...||..:.....|......||
Mouse   212 TARPPGEAGEEAKKGRALNKPQKG-LNHDLPRRHSMDRQNSQEKTVGS----------------- 258

  Fly   296 TNNVLGLDLRARAGSLSSSGAGSGSTSPSDSQSSGEISVSPVQQLLPQQQQQQQQSLLIQPLGPA 360
                            ::.||.|...||..|..:|...:||.....|:..:.         ||
Mouse   259 ----------------AAYGARSPCGSPGQSPPTGYSILSPAHFSGPRSSRY---------LG-- 296

  Fly   361 FGSNLLQNGLGLSKNLLIAPQQQQQQQLQQQQQQQNNLPALANISNFKPLASYEQQQLVQQQKNK 425
               ..|:|.:.|                   :..:..:|......|    |.::
Mouse   297 ---EFLKNAIHL-------------------EPHKKAVPGGHVFRN----AHFD----------- 324

  Fly   426 EVELYSDRVRSTSGCNGI-----FSRRLDFSS-FNLLPKTRLNSYQVKIEDEGNHG-NDETRLFI 483
                ||....|.......     |.||||.|. ...:|:.:||::.|::||:...| .::.|.||
Mouse   325 ----YSSAGLSVHRAGHFDTPVQFLRRLDLSELLTHIPRHKLNTFHVRMEDDAQVGQGEDLRKFI 385

  Fly   484 LSSLAQSQMSRVACILCEEPLLVFDRYPLVDGSFFLSPKQHSSGCIEVKY------EGRTLYLTC 542
            |::|:.|..:.|.|.||...|.||:::|||||:.||||.:|.    |::|      :||.::|..
Mouse   386 LAALSASHRNVVNCALCHRALPVFEQFPLVDGTLFLSPSRHD----EIEYDVPCHLQGRLMHLYA 446

  Fly   543 VCMSCLDGTSSSRAINCRFCKEPWDGSSLVLGTMYAYDIFAAMPCCAERFKCNNCFKMLMHPQQR 607
            ||:.||:|.   ..|.|..||..||||...|||||.|||.||.|||..|..|.:|.|.::..:..
Mouse   447 VCVDCLEGV---HKIICIKCKSRWDGSWHQLGTMYTYDILAASPCCQARLNCKHCGKPVIDVRIG 508

  Fly   608 LSFYSDYSHGVTCPYCNTQDTHFVKPLT 635
            :.::|:||:...||:|...|.|||||.:
Mouse   509 MQYFSEYSNVQQCPHCGNLDYHFVKPFS 536

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
heca	NP_788768.1	HECA	70..172	CDD:464667	45/116 (39%)
		Headcase	436..634	CDD:464967	83/210 (40%)
Heca	NP_001028604.1	HECA	95..192	CDD:464667	43/103 (42%)
		Headcase	341..536	CDD:464967	83/201 (41%)