DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9733 and gzma

DIOPT Version :9

Sequence 1:	NP_651784.2	Gene:	CG9733 / 43601	FlyBaseID:	FBgn0039759	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	XP_001335166.1	Gene:	gzma / 795070	ZFINID:	ZDB-GENE-091204-156	Length:	257	Species:	Danio rerio

Alignment Length:	266	Identity:	75/266 - (28%)
Similarity:	117/266 - (43%)	Gaps:	46/266 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   153 CGGVGIRNRIYDGQDTDVNEFPWMVLLEYRRRSGNGLSTACAGSLINRRYVLTAAHCLTGRIERE 217
            |..|.    |..|:|.. ....|||.::..:      :..|.|.||::.:|||||||
Zfish    23 CSDVS----IVGGKDVK-KALSWMVSIQVNQ------NHKCGGILIHKEWVLTAAHC-------- 68

  Fly   218 VGTLVSVRLGEHDTRTAVDCPPGGGSCSPEVQRLGFEEIRVHERYSEKASNQVHDIGLIRMERNV 282
                      :.|:.::|....|..|.|...||:......:.|.:::|....  ||.|||:.:.|
Zfish    69 ----------KEDSYSSVTVLIGSLSLSKGSQRIAIHNYEIPETFNKKTKKD--DIMLIRLSKKV 121

  Fly   283 RYSDNIQPICLPSSVGLESRQSGQQFTVAGWGRTLKMARSAVK--QKVTVNYVDPAKCRQRFSQI 345
            :    .:|..:|...  :..|.|.:..|.|||.|....:.|..  |.:.|..||..:|.:.:::.
Zfish   122 K----AKPYKIPKKE--KDVQPGTKCVVRGWGTTDYKGKQASDKLQMLEVLVVDRVQCNRYYNRN 180

  Fly   346 KVNLEPTQLCAGG-QFRKDSCDGDSGGPLMRFRDESWVLEGIVSFGYKCGLKDWPGVYTNVAAYD 409
            .| :....||||. |..:.:|.|||||||...::    |.|::|..:.||....|.|||.::...
Zfish   181 PV-ITKDMLCAGNTQQHRGTCLGDSGGPLECEKN----LVGVLSGSHGCGDPKKPTVYTLLSKRH 240

  Fly   410 I-WIRQ 414
            | ||.:
Zfish   241 ITWINK 246

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9733	NP_651784.2	CLIP	25..78	CDD:288855
		Tryp_SPc	161..412	CDD:214473	71/254 (28%)
		Tryp_SPc	162..415	CDD:238113	73/257 (28%)
gzma	XP_001335166.1	Tryp_SPc	28..247	CDD:238113	73/257 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587283
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930