DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9733 and TPSB2

DIOPT Version :9

Sequence 1:	NP_651784.2	Gene:	CG9733 / 43601	FlyBaseID:	FBgn0039759	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	NP_077078.5	Gene:	TPSB2 / 64499	HGNCID:	14120	Length:	275	Species:	Homo sapiens

Alignment Length:	277	Identity:	83/277 - (29%)
Similarity:	125/277 - (45%)	Gaps:	36/277 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   151 PSCGGVGIRNRIYDGQDTDVNEFPWMVLLEYRRRSGNGLSTACAGSLINRRYVLTAAHCLTGRIE 215
            |:.|....|..|..||:...:::||.|.|..|.|.....   |.||||:.::|||||||    :.
Human    20 PAPGQALQRVGIVGGQEAPRSKWPWQVSLRVRDRYWMHF---CGGSLIHPQWVLTAAHC----VG 77

  Fly   216 REVGTLVSVRLGEHDTRTAVDCPPGGGSCSPEVQRLGFEEIRVHERYSEKASNQV-HDIGLIRME 279
            .:|..|.::|:...:.....           :.|.|....|.||.::   .:.|: .||.|:.:|
Human    78 PDVKDLAALRVQLREQHLYY-----------QDQLLPVSRIIVHPQF---YTAQIGADIALLELE 128

  Fly   280 RNVRYSDNIQPICLPSSVGLESRQSGQQFTVAGWGRTLKMAR-------SAVKQKVTVNYVDPAK 337
            ..|..|.::..:.||.:  .|:...|....|.|||......|       ..||..:..|::..||
Human   129 EPVNVSSHVHTVTLPPA--SETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAK 191

  Fly   338 CR---QRFSQIKVNLEPTQLCAGGQFRKDSCDGDSGGPLMRFRDESWVLEGIVSFGYKCGLKDWP 399
            ..   .....::: :....||||.. |:|||.|||||||:...:.:|:..|:||:|..|...:.|
Human   192 YHLGAYTGDDVRI-VRDDMLCAGNT-RRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRP 254

  Fly   400 GVYTNVAAYDIWIRQNV 416
            |:||.|..|..||...|
Human   255 GIYTRVTYYLDWIHHYV 271

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9733	NP_651784.2	CLIP	25..78	CDD:288855
		Tryp_SPc	161..412	CDD:214473	77/261 (30%)
		Tryp_SPc	162..415	CDD:238113	79/263 (30%)
TPSB2	NP_077078.5	Tryp_SPc	31..268	CDD:238113	78/261 (30%)
TPSB2	NP_077078.5	Tryp_SPc	31..267	CDD:214473	77/260 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152785
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840