DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9733 and prss60.3

DIOPT Version :9

Sequence 1:	NP_651784.2	Gene:	CG9733 / 43601	FlyBaseID:	FBgn0039759	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	XP_002662541.2	Gene:	prss60.3 / 335152	ZFINID:	ZDB-GENE-030131-7092	Length:	330	Species:	Danio rerio

Alignment Length:	280	Identity:	85/280 - (30%)
Similarity:	127/280 - (45%)	Gaps:	40/280 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   147 LPQPPSCGGVGIRNRIYDGQDTDVNEFPWMVLLEYRRRSGNGLSTACAGSLINRRYVLTAAHCLT 211
            |.|...||...:..||..|.:.....:||.|.|...:..|:    .|.||||:..:||||||||:
Zfish    21 LSQLNVCGQAPLNTRIVGGVNASPGSWPWQVSLHSPKYGGH----FCGGSLISSEWVLTAAHCLS 81

  Fly   212 GRIEREVGTLVSVRLGEHDTRTAVDCPPGGGSCSPEVQRLGFEEIR------VHERYSEKASNQV 270
            |..|    |.:.|.||.. |:..::.               :|..|      ||..|:...::
Zfish    82 GVSE----TTLVVYLGRR-TQQGINI---------------YETSRNVAKSFVHSSYNSNTND-- 124

  Fly   271 HDIGLIRMERNVRYSDNIQPICLPSSVGLESRQSGQQFTVAGWG---RTLKMARSAVKQKVTVNY 332
            :||.|:|:...|.:::.|:|:||.:...:.|  :|....:.|||   ..:.:....:.|:..:..
Zfish   125 NDIALLRLSSAVTFTNYIRPVCLAAQNSVYS--AGTSSWITGWGDIQAGVNLPAPGILQETMIPV 187

  Fly   333 VDPAKCRQRFSQIKVNLEPTQLCAG-GQFRKDSCDGDSGGPLMRFRDESWVLEGIVSFGYKCGLK 396
            |...:|........|.  ...:||| .|..||:|.||||||::......||..||.|:||.|...
Zfish   188 VANDRCNALLGSGTVT--NNMICAGLTQGGKDTCQGDSGGPMVTRLCTVWVQAGITSWGYGCADP 250

  Fly   397 DWPGVYTNVAAYDIWIRQNV 416
            :.|||||.|:.|..||...:
Zfish   251 NSPGVYTRVSQYQSWISSKI 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9733	NP_651784.2	CLIP	25..78	CDD:288855
		Tryp_SPc	161..412	CDD:214473	79/260 (30%)
		Tryp_SPc	162..415	CDD:238113	80/262 (31%)
prss60.3	XP_002662541.2	Tryp_SPc	36..269	CDD:238113	80/262 (31%)
prss60.3	XP_002662541.2	Somatomedin_B	294..328	CDD:321959
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587321
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930