Protein Alignment CG9733 and HPN

DIOPT Version :10

• Sequence 1: NP_651784.2
• Gene: CG9733 / 43601
• FlyBaseID: FBgn0039759
• Length: 418
• Species: Drosophila melanogaster
• Sequence 2: NP_002142.1
• Gene: HPN / 3249
• HGNCID: 5155
• Length: 417
• Species: Homo sapiens
• Alignment Length: 287
• Identity: 98/287 - (34%)
• Similarity: 132/287 - (45%)
• Gaps: 53/287 - (18%)

  Fly   153 CGGVGIR----NRIYDGQDTDVNEFPWMVLLEYRRRSGNGLSTACAGSLINRRYVLTAAHCLTGR 213
            |...|.|    :||..|:||.:..:||.|.|.|   .|..|   |.|||::..:|||||||...|
Human   150 CQDCGRRKLPVDRIVGGRDTSLGRWPWQVSLRY---DGAHL---CGGSLLSGDWVLTAAHCFPER 208

  Fly   214 IEREVGTLVSVRLGEHDTRTAVDCPPGGGSCSPEVQRLGFEEIRVHERY-------SEKASNQVH 271
              ..|.:...|..|      ||      ...||...:||.:.:..|..|       ||:.||
Human   209 --NRVLSRWRVFAG------AV------AQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSN--- 256

  Fly   272 DIGLIRMERNVRYSDNIQPICLPSSVGLESRQSGQQFTVAGWGRTLKMARSA-VKQKVTVNYVDP 335
            ||.|:.:...:..::.|||:|||::.  ::...|:..||.|||.|....:.| |.|:..|..:..
Human   257 DIALVHLSSPLPLTEYIQPVCLPAAG--QALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISN 319

  Fly   336 AKCRQR---FSQIKVNLEPTQLCAG---GQFRKDSCDGDSGGPLM----RFRDESWVLEGIVSFG 390
            ..|...   .:|||    |...|||   |..  |:|.||||||.:    ..|...|.|.||||:|
Human   320 DVCNGADFYGNQIK----PKMFCAGYPEGGI--DACQGDSGGPFVCEDSISRTPRWRLCGIVSWG 378

  Fly   391 YKCGLKDWPGVYTNVAAYDIWIRQNVR 417
            ..|.|...|||||.|:.:..||.|.::
Human   379 TGCALAQKPGVYTKVSDFREWIFQAIK 405

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9733	NP_651784.2	CLIP	25..78	CDD:463440
		Tryp_SPc	162..415	CDD:238113	93/270 (34%)
HPN	NP_002142.1	Hepsin-SRCR	51..159	CDD:462736	3/8 (38%)
		Tryp_SPc	163..400	CDD:238113	91/267 (34%)