DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9733 and f10

DIOPT Version :9

Sequence 1:	NP_651784.2	Gene:	CG9733 / 43601	FlyBaseID:	FBgn0039759	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	NP_958870.3	Gene:	f10 / 282670	ZFINID:	ZDB-GENE-021206-9	Length:	504	Species:	Danio rerio

Alignment Length:	272	Identity:	88/272 - (32%)
Similarity:	138/272 - (50%)	Gaps:	37/272 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   146 LLPQPPSCGGVGIRNRIYDGQDTDVNEFPWMVLLEYRRRSGNGLSTACAGSLINRRYVLTAAHCL 210
            :||...:.|.    .||.:|.:....:.||..||......|     .|.|:::...::|:||||:
Zfish   233 ILPVVSTAGD----GRIVNGVECPPGDCPWQALLINENNMG-----FCGGTILTEHFILSAAHCM 288

  Fly   211 TGRIEREVGTLVSVRLGEHDTRTAVDCPPGGGSCSPEVQRLGFEEIRVHERYSEKASNQVHDIGL 275
            ...:.      :.|.:||:||..     |.|...:.:|     :||.:|:.|.....:  :||.|
Zfish   289 NESLS------IRVVVGEYDTLV-----PEGREATHDV-----DEILIHKNYQPDTYH--NDIAL 335

  Fly   276 IRMERNVRYSDNIQPICLPSSVGLESRQSGQQ--FTVAGWGRTLKMA-RSAVKQKVTVNYVDPAK 337
            |::.:.::::..|.|.||| .:....|...||  ..|:|:||..:.. .|.:.||:||.||:.||
Zfish   336 IKLSKPIKFTKYIIPACLP-EMKFAERVLMQQDDGLVSGFGRVREGGLSSTILQKLTVPYVNRAK 399

  Fly   338 CRQRFSQIKVNLEPTQLCAG-GQFRKDSCDGDSGGP-LMRFRDESWVLEGIVSFGYKCGLKDWPG 400
            |.:. |..|::  ....||| .|..||:|.|||||| :.||:: :|.:.|:||:|..|..|...|
Zfish   400 CIES-SNFKIS--GRMFCAGYDQEEKDACQGDSGGPHVTRFKN-TWFITGVVSWGEGCARKGKYG 460

  Fly   401 VYTNVAAYDIWI 412
            |||.|:.|.:||
Zfish   461 VYTQVSKYIMWI 472

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9733	NP_651784.2	CLIP	25..78	CDD:288855
		Tryp_SPc	161..412	CDD:214473	83/255 (33%)
		Tryp_SPc	162..415	CDD:238113	84/256 (33%)
f10	NP_958870.3	GLA	19..82	CDD:214503
		EGF_CA	83..119	CDD:238011
		FXa_inhibition	126..161	CDD:291342
		Tryp_SPc	244..472	CDD:214473	83/255 (33%)
		Tryp_SPc	245..474	CDD:238113	84/256 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D402896at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920