DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9733 and TPSD1

DIOPT Version :9

Sequence 1:	NP_651784.2	Gene:	CG9733 / 43601	FlyBaseID:	FBgn0039759	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	NP_036349.1	Gene:	TPSD1 / 23430	HGNCID:	14118	Length:	242	Species:	Homo sapiens

Alignment Length:	236	Identity:	66/236 - (27%)
Similarity:	101/236 - (42%)	Gaps:	38/236 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   151 PSCGGVGIRNRIYDGQDTDVNEFPWMVLLEYRRRSGNGLSTACAGSLINRRYVLTAAHCLTGRIE 215
            |:.|....:..|..||:...:::||.|.|..|   |......|.||||:.::|||||||    :|
Human    27 PAPGQALQQTGIVGGQEAPRSKWPWQVSLRVR---GPYWMHFCGGSLIHPQWVLTAAHC----VE 84

  Fly   216 REVGTLVSVRLGEHDTRTAVDCPPGGGSCSPEVQRLGFEEIRVHERYSEKASNQVHDIGLIRMER 280
            .::..|.::|:...:.....           :.|.|....|.||.::....:..  ||.|:.:|.
Human    85 PDIKDLAALRVQLREQHLYY-----------QDQLLPVSRIIVHPQFYIIQTGA--DIALLELEE 136

  Fly   281 NVRYSDNIQPICLPSSVGLESRQSGQQFTVAGWG---RTLKMARSAVKQKVTVNYVDPAKCRQRF 342
            .|..|.:|..:.||.:  .|:...|....|.|||   ..:.:......::|.|..|:...|...:
Human   137 PVNISSHIHTVTLPPA--SETFPPGMPCWVTGWGDVDNNVHLPPPYPLKEVEVPVVENHLCNAEY 199

  Fly   343 S---------QIKVNLEPTQLCAGGQFRKDSCDGDSGGPLM 374
            .         ||   :....||||.: ..|||.|||||||:
Human   200 HTGLHTGHSFQI---VRDDMLCAGSE-NHDSCQGDSGGPLV 236

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9733	NP_651784.2	CLIP	25..78	CDD:288855
		Tryp_SPc	161..412	CDD:214473	64/226 (28%)
		Tryp_SPc	162..415	CDD:238113	64/225 (28%)
TPSD1	NP_036349.1	Tryp_SPc	38..242	CDD:238113	64/225 (28%)
TPSD1	NP_036349.1	Tryp_SPc	38..240	CDD:214473	64/225 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152790
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840