DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9733 and LOC100004411

DIOPT Version :9

Sequence 1:	NP_651784.2	Gene:	CG9733 / 43601	FlyBaseID:	FBgn0039759	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	XP_001343728.4	Gene:	LOC100004411 / 100004411	-ID:	-	Length:	494	Species:	Danio rerio

Alignment Length:	432	Identity:	119/432 - (27%)
Similarity:	167/432 - (38%)	Gaps:	85/432 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 NPNQTPGLC-----VLINECQTLYSVLKRATLTDQEKSFIK------------------SSACGR 68
            ||.|..|:|     |....|..|||    .|..:.|.|..|                  ..:|..
Zfish    93 NPCQNGGMCRENRGVQECLCPPLYS----GTNCETEVSDCKYKNGGCLHYCSQNETAGVECSCAD 153

  Fly    69 G----------SNNQPYVCCTQDTGYVRIQRQD---RTFPDYGAFGGDWEEERPQSFVFPRQERR 120
            |          |....|.|..|.||.:..:..|   .|..||.        ....|...|   ..
Zfish   154 GYQLDEDRHSCSPAVQYPCGKQWTGGIMSRSLDDVSHTHADYA--------NHTHSSTSP---SH 207

  Fly   121 PWSFGNQPATSRTPFRKSSTSDGSSLLPQPPSCGGVGIRNRIYDGQDTDVNEFPWMVLLEYRRRS 185
            |.........:.|...::..:....||.......|.....||..||.......||.|||  ||..
Zfish   208 PLHHNRSALENSTHQNQTELTAPDQLLDTGSDFTGGNEDTRIVGGQLQRQGGSPWQVLL--RRED 270

  Fly   186 GNGLSTACAGSLINRRYVLTAAHCLTGRIEREVGTLVSVRLGEHDTRTAVDCPPGGGSCSPEVQR 250
            ..|.   |.|||||:|:|:||||||.       .|...:.:|::|....          ..:.|:
Zfish   271 EYGF---CGGSLINQRWVITAAHCLQ-------QTPHHITIGDYDKMRP----------DKDEQK 315

  Fly   251 LGFEEIRVHERYSEKASNQVHDIGLIRMERNVRYSDNIQPICLPSSVGLESR--QSGQQFTVAGW 313
            :..|:|..|..|.|...:.  ||.|:.:...|.......|.|||.: .|..|  :.|:|..|:||
Zfish   316 ITVEKIIPHPHYHEYTFDS--DIALLYLSSAVTLGPFASPACLPDA-NLAERLMKPGEQGLVSGW 377

  Fly   314 GRTLKMARSA-VKQKVTVNYVDPAKCRQRFSQIKVNLEPTQLCAGGQFRK-DSCDGDSGGP-LMR 375
            |.|..:.||: ..:||.:..|:...|.....||   :.....|||....: |:|.|||||| ::.
Zfish   378 GSTHYLQRSSRFLRKVQLPVVEQKSCINSTEQI---ITDNMFCAGFLMEEMDACTGDSGGPFIVN 439

  Fly   376 FRDESWVLEGIVSFGYKCGLKDWPGVYTNVAAYDIWIRQNVR 417
            :|. :|.|.|:||:|.:|..:...||||.:..|..||::.::
Zfish   440 YRG-TWFLTGVVSWGERCASQGKYGVYTRLGNYLSWIQEEMK 480

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9733	NP_651784.2	CLIP	25..78	CDD:288855	18/83 (22%)
		Tryp_SPc	161..412	CDD:214473	84/255 (33%)
		Tryp_SPc	162..415	CDD:238113	85/257 (33%)
LOC100004411	XP_001343728.4	GLA	22..85	CDD:214503
		EGF_CA	86..122	CDD:238011	11/32 (34%)
		FXa_inhibition	128..164	CDD:291342	3/35 (9%)
		Tryp_SPc	248..475	CDD:214473	84/255 (33%)
		Tryp_SPc	249..477	CDD:238113	85/256 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D402896at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920