Protein Alignment CG9737 and TMPRSS2

DIOPT Version :10

• Sequence 1: NP_651783.1
• Gene: CG9737 / 43600
• FlyBaseID: FBgn0039758
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: NP_001128571.1
• Gene: TMPRSS2 / 7113
• HGNCID: 11876
• Length: 529
• Species: Homo sapiens
• Alignment Length: 283
• Identity: 85/283 - (30%)
• Similarity: 130/283 - (45%)
• Gaps: 60/283 - (21%)

  Fly   142 CGKQVT----NRIYGGEIAELDEFPWLALLVYNSNDYGCSGALIDDRHILTAAHCVQGEGVRDRQ 202
            ||..:.    :||.|||.|....:||...| :..|.:.|.|::|....|:||||||:
Human   281 CGVNLNSSRQSRIVGGESALPGAWPWQVSL-HVQNVHVCGGSIITPEWIVTAAHCVE-------- 336

  Fly   203 GLKHVRLGEFNVKTEPDCIEEPNYLSCADAALDIAY---------EKIHVHPEYKEFSNYKYNDI 258
                          :|  :..|.:.:.....|..::         ||:..||.|.  |..|.|||
Human   337 --------------KP--LNNPWHWTAFAGILRQSFMFYGAGYQVEKVISHPNYD--SKTKNNDI 383

  Fly   259 AIIRLKHPVSFTHFVMPICLPNKSEPLTLAEGQMFSVSGWGRTDLFNKYFINIHSPIKLKLRIPY 323
            |:::|:.|::|...|.|:||||..  :.|...|:..:||||.|:...|     .|.:....::..
Human   384 ALMKLQKPLTFNDLVKPVCLPNPG--MMLQPEQLCWISGWGATEEKGK-----TSEVLNAAKVLL 441

  Fly   324 VSNENCTK--ILEGFGVRLGPKQICAGGEFAK---DTCAGDSGGPLMYFDRQHSRWVAYGVVSYG 383
            :..:.|..  :.:..   :.|..||||  |.:   |:|.|||||||:  ..:::.|...|..|:|
Human   442 IETQRCNSRYVYDNL---ITPAMICAG--FLQGNVDSCQGDSGGPLV--TSKNNIWWLIGDTSWG 499

  Fly   384 FTQCGMAGKPAVYTNVAEYTDWI 406
             :.|..|.:|.||.||..:||||
Human   500 -SGCAKAYRPGVYGNVMVFTDWI 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9737	NP_651783.1	CLIP	28..89	CDD:463440
		Tryp_SPc	149..406	CDD:214473	81/270 (30%)
TMPRSS2	NP_001128571.1	LDLa	150..185	CDD:238060
		SRCR_2	190..283	CDD:464747	1/1 (100%)
		Tryp_SPc	293..524	CDD:238113	82/271 (30%)