DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9737 and prss60.2

DIOPT Version :9

Sequence 1:	NP_651783.1	Gene:	CG9737 / 43600	FlyBaseID:	FBgn0039758	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	NP_001099071.1	Gene:	prss60.2 / 541408	ZFINID:	ZDB-GENE-050320-109	Length:	328	Species:	Danio rerio

Alignment Length:	297	Identity:	98/297 - (32%)
Similarity:	139/297 - (46%)	Gaps:	67/297 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   139 LNECGKQVTN-RIYGGEIAELDEFPWLALLVYNSNDYG---CSGALIDDRHILTAAHCVQGE--- 196
            ||.||:...| ||.||..|....:||...|  .|..||   |.|:||....:||||||:.|.
Zfish    22 LNVCGQAPLNSRIVGGVNAPEGSWPWQVSL--QSPRYGGHFCGGSLISSEWVLTAAHCLPGVSES 84

  Fly   197 ------GVRDRQGLKHVRLGEFNVKTEPDCIEEPNYLSCADAALDIAYEKIHVHPEYKEFSNYKY 255
                  |.|.:||          |.|.             :.:.::|  ||.||..|.  ||...
Zfish    85 SLVVYLGRRTQQG----------VNTH-------------ETSRNVA--KIIVHSSYN--SNTND 122

  Fly   256 NDIAIIRLKHPVSFTHFVMPICLPNKSEPLTLAEGQMFS------VSGWGRTDLFNKYFINIHSP 314
            ||||::||...|:|..::.|:||        .|:..::|      ::|||..    :..:|:.:|
Zfish   123 NDIALLRLSSAVTFNDYIRPVCL--------AAQNSVYSAGTSSWITGWGDV----QAGVNLPAP 175

  Fly   315 -IKLKLRIPYVSNENCTKILEGFGVRLGPKQICAG-GEFAKDTCAGDSGGPLMYFDRQHSRWVAY 377
             |..:..||.|:|:.|...| |.|. :....|||| .:..||||.||||||::  .|..:.|:..
Zfish   176 GILQETMIPVVANDRCNAQL-GSGT-VTNNMICAGLAKGGKDTCQGDSGGPMV--TRLCTVWIQA 236

  Fly   378 GVVSYGFTQCGMAGKPAVYTNVAEYTDWIDSVVQQRK 414
            |:.|:|: .|.....|.|||.|::|..||.|.:.|.:
Zfish   237 GITSWGY-GCADPNSPGVYTRVSQYQSWISSKISQNQ 272

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9737	NP_651783.1	CLIP	28..89	CDD:288855
		Tryp_SPc	149..406	CDD:214473	89/276 (32%)
		Tryp_SPc	150..409	CDD:238113	90/278 (32%)
prss60.2	NP_001099071.1	Tryp_SPc	33..264	CDD:214473	89/276 (32%)
		Tryp_SPc	34..267	CDD:238113	90/278 (32%)
		Somatomedin_B	296..326	CDD:295334
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587422
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840