DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9737 and prss60.3

DIOPT Version :9

Sequence 1:	NP_651783.1	Gene:	CG9737 / 43600	FlyBaseID:	FBgn0039758	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	XP_002662541.2	Gene:	prss60.3 / 335152	ZFINID:	ZDB-GENE-030131-7092	Length:	330	Species:	Danio rerio

Alignment Length:	297	Identity:	100/297 - (33%)
Similarity:	143/297 - (48%)	Gaps:	67/297 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   139 LNECGKQVTN-RIYGGEIAELDEFPWLALLVYNSNDYG---CSGALIDDRHILTAAHCVQGE--- 196
            ||.||:...| ||.||..|....:||...|  :|..||   |.|:||....:||||||:.|.
Zfish    24 LNVCGQAPLNTRIVGGVNASPGSWPWQVSL--HSPKYGGHFCGGSLISSEWVLTAAHCLSGVSET 86

  Fly   197 ------GVRDRQGLKHVRLGEFNVKTEPDCIEEPNYLSCADAALDIAYEKIHVHPEYKEFSNYKY 255
                  |.|.:||:        |:           |.:..:.|      |..||..|.  ||...
Zfish    87 TLVVYLGRRTQQGI--------NI-----------YETSRNVA------KSFVHSSYN--SNTND 124

  Fly   256 NDIAIIRLKHPVSFTHFVMPICLPNKSEPLTLAEGQMFS------VSGWGRTDLFNKYFINIHSP 314
            ||||::||...|:||:::.|:||        .|:..::|      ::|||  |:  :..:|:.:|
Zfish   125 NDIALLRLSSAVTFTNYIRPVCL--------AAQNSVYSAGTSSWITGWG--DI--QAGVNLPAP 177

  Fly   315 -IKLKLRIPYVSNENCTKILEGFGVRLGPKQICAG-GEFAKDTCAGDSGGPLMYFDRQHSRWVAY 377
             |..:..||.|:|:.|..:| |.|. :....|||| .:..||||.||||||::  .|..:.||..
Zfish   178 GILQETMIPVVANDRCNALL-GSGT-VTNNMICAGLTQGGKDTCQGDSGGPMV--TRLCTVWVQA 238

  Fly   378 GVVSYGFTQCGMAGKPAVYTNVAEYTDWIDSVVQQRK 414
            |:.|:|: .|.....|.|||.|::|..||.|.:...|
Zfish   239 GITSWGY-GCADPNSPGVYTRVSQYQSWISSKISLNK 274

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9737	NP_651783.1	CLIP	28..89	CDD:288855
		Tryp_SPc	149..406	CDD:214473	91/276 (33%)
		Tryp_SPc	150..409	CDD:238113	92/278 (33%)
prss60.3	XP_002662541.2	Tryp_SPc	36..269	CDD:238113	92/278 (33%)
prss60.3	XP_002662541.2	Somatomedin_B	294..328	CDD:321959
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587421
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.930