DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9737 and f10

DIOPT Version :9

Sequence 1:	NP_651783.1	Gene:	CG9737 / 43600	FlyBaseID:	FBgn0039758	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	NP_958870.3	Gene:	f10 / 282670	ZFINID:	ZDB-GENE-021206-9	Length:	504	Species:	Danio rerio

Alignment Length:	390	Identity:	109/390 - (27%)
Similarity:	169/390 - (43%)	Gaps:	99/390 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 CEVEQQVSEAQGSYESLVCCPANG------------QD-----YLFPVLQFSKFEYRRFLDVTAR 117
            |||.:         :::||..|||            ||     .::|....|.|.:...:..:..
Zfish   137 CEVME---------KNVVCSCANGYELAPNGKSCQSQDPFKCGVIYPKKTRSIFFHTPNITESEN 192

  Fly   118 FKRKKLKRRIQTVEPSSGFNLLNECGKQVTN-------------------------RIYGGEIAE 157
            .:..:|:   .|:||.  :|..|....|..:                         ||..|....
Zfish   193 EEETELE---ATIEPV--YNHSNPLNNQTDSMFGLHELEIIEEEPILPVVSTAGDGRIVNGVECP 252

  Fly   158 LDEFPWLALLVYNSNDYG-CSGALIDDRHILTAAHCVQGEGVRDRQGLKHVRLGEFNVKTEPDCI 221
            ..:.||.|||: |.|:.| |.|.::.:..||:||||: .|.:..|     |.:||::.     .:
Zfish   253 PGDCPWQALLI-NENNMGFCGGTILTEHFILSAAHCM-NESLSIR-----VVVGEYDT-----LV 305

  Fly   222 EEPNYLSCADAALDIAYEKIHVHPEYKEFSNYKYNDIAIIRLKHPVSFTHFVMPICLPNKSEPLT 286
            .|..     :|..|:  ::|.:|..|:. ..| :||||:|:|..|:.||.:::|.|||.    :.
Zfish   306 PEGR-----EATHDV--DEILIHKNYQP-DTY-HNDIALIKLSKPIKFTKYIIPACLPE----MK 357

  Fly   287 LAEGQMFS-----VSGWGRTDLFNKYFINIHSPIKLKLRIPYVSNENCTKILEGFGVRLGPKQIC 346
            .||..:..     |||:||....     .:.|.|..||.:|||:...|   :|....::..:..|
Zfish   358 FAERVLMQQDDGLVSGFGRVREG-----GLSSTILQKLTVPYVNRAKC---IESSNFKISGRMFC 414

  Fly   347 AG-GEFAKDTCAGDSGGPLMYFDRQHSRWVAYGVVSYGFTQCGMAGKPAVYTNVAEYTDWIDSVV 410
            || .:..||.|.||||||  :..|..:.|...||||:| ..|...||..|||.|::|..||::.:
Zfish   415 AGYDQEEKDACQGDSGGP--HVTRFKNTWFITGVVSWG-EGCARKGKYGVYTQVSKYIMWINNAM 476

Fly 411 410
Zfish 477 476

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9737	NP_651783.1	CLIP	28..89	CDD:288855	4/18 (22%)
		Tryp_SPc	149..406	CDD:214473	87/263 (33%)
		Tryp_SPc	150..409	CDD:238113	88/265 (33%)
f10	NP_958870.3	GLA	19..82	CDD:214503
		EGF_CA	83..119	CDD:238011
		FXa_inhibition	126..161	CDD:291342	8/32 (25%)
		Tryp_SPc	244..472	CDD:214473	87/263 (33%)
		Tryp_SPc	245..474	CDD:238113	88/264 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D402896at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920