DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9737 and TPSG1

DIOPT Version :9

Sequence 1:	NP_651783.1	Gene:	CG9737 / 43600	FlyBaseID:	FBgn0039758	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	XP_011520748.1	Gene:	TPSG1 / 25823	HGNCID:	14134	Length:	346	Species:	Homo sapiens

Alignment Length:	282	Identity:	90/282 - (31%)
Similarity:	131/282 - (46%)	Gaps:	42/282 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   132 PSSGFNLLNECGK-QVTN---RIYGGEIAELDEFPWLALLVYNSNDYGCSGALIDDRHILTAAHC 192
            ||| |:|  .||: ||::   ||.||..|....:||.|.|... ..:.|.|:|:..:.:||||||
Human    44 PSS-FDL--GCGRPQVSDAGGRIVGGHAAPAGAWPWQASLRLR-RVHVCGGSLLSPQWVLTAAHC 104

  Fly   193 VQGE-GVRDRQGLKHVRLGEFNVKTEPDCIEEPNYLSCADAALDIAYEKIHVHPEYKEFSNYKYN 256
            ..|. ...|.|    |.|||..:...|       :.|.....:      :|..|..:..::   .
Human   105 FSGSLNSSDYQ----VHLGELEITLSP-------HFSTVRQII------LHSSPSGQPGTS---G 149

  Fly   257 DIAIIRLKHPVSFTHFVMPICLPNKSEPLTLAEGQMFSVSGWGRTDLFNKYFINIHSPIKLK-LR 320
            |||::.|..||:.:..::|:|||..|:  ....|....|:|||    :.:....:..|..|: ::
Human   150 DIALVELSVPVTLSSRILPVCLPEASD--DFCPGIRCWVTGWG----YTREGEPLPPPYSLREVK 208

  Fly   321 IPYVSNENCTKILEG-FGVRLGPKQICAGGEFAKDTCAGDSGGPLMYFDRQHSRWVAYGVVSYGF 384
            :..|..|.|.:...| .|..|.|..:||.|  ..|.|..||||||:.  :.:..||..|.||:|
Human   209 VSVVDTETCRRDYPGPGGSILQPDMLCARG--PGDACQDDSGGPLVC--QVNGAWVQAGTVSWG- 268

  Fly   385 TQCGMAGKPAVYTNVAEYTDWI 406
            ..||...:|.|||.|..|.:||
Human   269 EGCGRPNRPGVYTRVPAYVNWI 290

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9737	NP_651783.1	CLIP	28..89	CDD:288855
		Tryp_SPc	149..406	CDD:214473	79/259 (31%)
		Tryp_SPc	150..409	CDD:238113	80/260 (31%)
TPSG1	XP_011520748.1	Tryp_SPc	62..290	CDD:214473	79/259 (31%)
TPSG1	XP_011520748.1	Tryp_SPc	63..293	CDD:238113	80/260 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152806
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.840