DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG9737 and F10

DIOPT Version :9

Sequence 1:NP_651783.1 Gene:CG9737 / 43600 FlyBaseID:FBgn0039758 Length:424 Species:Drosophila melanogaster
Sequence 2:NP_000495.1 Gene:F10 / 2159 HGNCID:3528 Length:488 Species:Homo sapiens


Alignment Length:457 Identity:125/457 - (27%)
Similarity:189/457 - (41%) Gaps:106/457 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly    14 CFYRFLALAEVLQECDIPNE----------TKRGVCLEVSRCKAYLQVRNATNLPA-EKVN---F 64
            |.|.  ...||.::.|..||          .:...|....:||..|.....|.|.. |..|   |
Human    62 CSYE--EAREVFEDSDKTNEFWNKYKDGDQCETSPCQNQGKCKDGLGEYTCTCLEGFEGKNCELF 124

  Fly    65 LKKVQC-----EVEQQVSEAQGSYESLVCCPANGQDYLFPVLQFSKFEYRRFLDVTARFK--RKK 122
            .:|: |     :.:|...|.|   .|:||..|.|         ::..:..:....|..:.  ::.
Human   125 TRKL-CSLDNGDCDQFCHEEQ---NSVVCSCARG---------YTLADNGKACIPTGPYPCGKQT 176

  Fly   123 LKRRIQTV---EPSSG----------------------FNLLN------ECGKQVTNRIYGGEIA 156
            |:||.::|   ..|||                      |:||:      |.|.....||.||:..
Human   177 LERRKRSVAQATSSSGEAPDSITWKPYDAADLDPTENPFDLLDFNQTQPERGDNNLTRIVGGQEC 241

  Fly   157 ELDEFPWLALLVYNSNDYGCSGALIDDRHILTAAHCV-QGEGVRDRQGLKHVRLGEFNVKTEPDC 220
            :..|.||.|||:...|:..|.|.::.:.:|||||||: |.:..:       ||:|:.|.:.|.. 
Human   242 KDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFK-------VRVGDRNTEQEEG- 298

  Fly   221 IEEPNYLSCADAALDIAYEKIHVHPEYKEFSNYKYN-DIAIIRLKHPVSFTHFVMPICLPNKS-E 283
                          ..|..::.|..::..|:...|: |||::|||.|::|...|.|.|||.:. .
Human   299 --------------GEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWA 349

  Fly   284 PLTLAEGQMFSVSGWGRTDLFNKYFINIHSPIKLK-LRIPYVSNENCTKILEGFGVRLGPKQICA 347
            ..||...:...|||:|||....:      ...:|| |.:|||...:| |:...|.:.  ....||
Human   350 ESTLMTQKTGIVSGFGRTHEKGR------QSTRLKMLEVPYVDRNSC-KLSSSFIIT--QNMFCA 405

  Fly   348 GGEF-AKDTCAGDSGGPLMYFDRQHSRWVAYGVVSYGFTQCGMAGKPAVYTNVAEYTDWIDSVVQ 411
            |.:. .:|.|.||||||  :..|....:...|:||:| ..|...||..:||.|..:..|||..::
Human   406 GYDTKQEDACQGDSGGP--HVTRFKDTYFVTGIVSWG-EGCARKGKYGIYTKVTAFLKWIDRSMK 467

  Fly   412 QR 413
            .|
Human   468 TR 469

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG9737NP_651783.1 CLIP 28..89 CDD:288855 19/79 (24%)
Tryp_SPc 149..406 CDD:214473 82/261 (31%)
Tryp_SPc 150..409 CDD:238113 84/263 (32%)
F10NP_000495.1 GLA 25..85 CDD:214503 7/24 (29%)
EGF_CA 86..122 CDD:238011 8/35 (23%)
FXa_inhibition 129..164 CDD:317114 9/46 (20%)
O-glycosylated at one site 183..203 4/19 (21%)
Tryp_SPc 235..464 CDD:238113 83/262 (32%)
O-glycosylated at one site 476..485
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D402896at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X11
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.920

Return to query results.
Submit another query.