DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9737 and Tpsb2

DIOPT Version :9

Sequence 1:	NP_651783.1	Gene:	CG9737 / 43600	FlyBaseID:	FBgn0039758	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	NP_034911.3	Gene:	Tpsb2 / 17229	MGIID:	96942	Length:	276	Species:	Mus musculus

Alignment Length:	272	Identity:	90/272 - (33%)
Similarity:	130/272 - (47%)	Gaps:	38/272 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   150 IYGGEIAELDEFPWLALLVYNSN--DYGCSGALIDDRHILTAAHCVQGEGVRDRQGLKHVRLGEF 212
            |.||..|...::||...|.:..|  .:.|.|:||..:.:||||||| |..::..| |..|:|.|
Mouse    32 IVGGHEASESKWPWQVSLRFKLNYWIHFCGGSLIHPQWVLTAAHCV-GPHIKSPQ-LFRVQLRE- 93

  Fly   213 NVKTEPDCIEEPNYLSCADAALDIAYEKIHVHPEYKEFSNYKYNDIAIIRLKHPVSFTHFVMPIC 277
                        .||...|..|.:  .:|.|||.|  ::.....|:|::.|:.||:.:..:.||.
Mouse    94 ------------QYLYYGDQLLSL--NRIVVHPHY--YTAEGGADVALLELEVPVNVSTHLHPIS 142

  Fly   278 LPNKSEPLTLAEGQMFSVSGWGRTDLFNKYFINIHSPIKLKLRIPYVSNENCTKILEGFGVRLGP 342
            ||..||  |...|....|:|||  |:.|...:....|:| ::::|.|.|..|.:... .|:..|.
Mouse   143 LPPASE--TFPPGTSCWVTGWG--DIDNDEPLPPPYPLK-QVKVPIVENSLCDRKYH-TGLYTGD 201

  Fly   343 K-------QICAGGEFAKDTCAGDSGGPLMYFDRQHSRWVAYGVVSYGFTQCGMAGKPAVYTNVA 400
            .       .:|||.. .:|:|.|||||||:.  :....|:..||||:| ..|....||.:||.|.
Mouse   202 DFPIVHDGMLCAGNT-RRDSCQGDSGGPLVC--KVKGTWLQAGVVSWG-EGCAQPNKPGIYTRVT 262

  Fly   401 EYTDWIDSVVQQ 412
            .|.|||...|.:
Mouse   263 YYLDWIHRYVPE 274

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9737	NP_651783.1	CLIP	28..89	CDD:288855
		Tryp_SPc	149..406	CDD:214473	87/264 (33%)
		Tryp_SPc	150..409	CDD:238113	89/267 (33%)
Tpsb2	NP_034911.3	Tryp_SPc	32..270	CDD:238113	89/266 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842868
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840