DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9743 and OLE1

DIOPT Version :9

Sequence 1:	NP_651781.1	Gene:	CG9743 / 43593	FlyBaseID:	FBgn0039756	Length:	420	Species:	Drosophila melanogaster
Sequence 2:	NP_011460.3	Gene:	OLE1 / 852825	SGDID:	S000003023	Length:	510	Species:	Saccharomyces cerevisiae

Alignment Length:	409	Identity:	116/409 - (28%)
Similarity:	190/409 - (46%)	Gaps:	64/409 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 NRSAAIVPNGGELKHRGHATDATSHTLVKDDDNLGYKEENAVYKEQQLLQQQDQTLKEAE---QV 91
            |:.|..:.||     .|....:.....|:.|.....|:.|.    .:||::.:|..:||:   .:
Yeast    42 NKKAPRIVNG-----FGSLMGSKEMVSVEFDKKGNEKKSNL----DRLLEKDNQEKEEAKTKIHI 97

  Fly    92 EEE----EEYHPQIRW---------PDLG------AQAFLHIGALYGLYQLFYANFYTFLWVVVT 137
            .|:    ..:|..:.|         |.:|      .:..||:...  |:.:||   |.
Yeast    98 SEQPWTLNNWHQHLNWLNMVLVCGMPMIGWYFALSGKVPLHLNVF--LFSVFY---YA------- 150

  Fly   138 VWVSGIGITAGAHRLWSHKSYTASLPLRILLAFAFSIAGQRDAYTWALDHRIHHKFSETDADPHN 202
              |.|:.||||.||||||:||:|..|||:..|.....:.:..|..|...|||||::::|..||::
Yeast   151 --VGGVSITAGYHRLWSHRSYSAHWPLRLFYAIFGCASVEGSAKWWGHSHRIHHRYTDTLRDPYD 213

  Fly   203 AKRGFFFAHVGWLFLTPHPKVVAKRKVIDMSDLEADAVCMFQRKYYIPLFALCSIILPVAVPWYF 267
            |:||.:::|:||:.|.|:||..|:..:.||:|   |....||.::||.|..|.:.::|..:..||
Yeast   214 ARRGLWYSHMGWMLLKPNPKYKARADITDMTD---DWTIRFQHRHYILLMLLTAFVIPTLICGYF 275

  Fly   268 WNEDLWMSFWINFNMRFTWTLNVAFFVNSVAHMYGNKPYDKNLMSTEAPIVSLLAMGEGWHNYHH 332
            :|:.:....:..| :|........|.:||:||..|.:|:|......:..|.:::..|||:||:||
Yeast   276 FNDYMGGLIYAGF-IRVFVIQQATFCINSLAHYIGTQPFDDRRTPRDNWITAIVTFGEGYHNFHH 339

  Fly   333 VFPWDYKTGEFGNYSLNITTGFIDFCAWLGLAKGRKSVSPD-----MVLRRAKKCGDGTRFLDDD 392
            .||.||:.. ...|..:.|...|...:.:|||...|..|.:     ::.:..||.......::
Yeast   340 EFPTDYRNA-IKWYQYDPTKVIIYLTSLVGLAYDLKKFSQNAIEEALIQQEQKKINKKKAKIN-- 401

  Fly   393 HAHKDPVWGFGDKDIPRED 411
                   ||....|:|..|
Yeast   402 -------WGPVLTDLPMWD 413

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9743	NP_651781.1	Delta9-FADS-like	130..368	CDD:239582	82/237 (35%)
CG9743	NP_651781.1	FA_desaturase	131..335	CDD:278890	72/203 (35%)
OLE1	NP_011460.3	OLE1	92..385	CDD:224316	95/311 (31%)
OLE1	NP_011460.3	CYB5	<408..510	CDD:227599	3/6 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	186	1.000	Domainoid score	I661
eggNOG	1	0.900	-	-		E1_COG1398
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	205	1.000	Inparanoid score	I832
Isobase	1	0.950	-	0.837287	Normalized mean entropy	S1208
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000495
OrthoInspector	1	1.000	-	-		otm46538
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X207
TreeFam	1	0.960	-	-
	10	9.770