DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9743 and Scd2

DIOPT Version :9

Sequence 1:	NP_651781.1	Gene:	CG9743 / 43593	FlyBaseID:	FBgn0039756	Length:	420	Species:	Drosophila melanogaster
Sequence 2:	NP_114029.1	Gene:	Scd2 / 83792	RGDID:	621177	Length:	358	Species:	Rattus norvegicus

Alignment Length:	348	Identity:	160/348 - (45%)
Similarity:	207/348 - (59%)	Gaps:	25/348 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 NGGE-LKHRGHATDATSHTLVKDDDNLGYKEENAVYKEQQLLQQQDQTLKEAEQVEEEEEYHPQI 101
            |||| .:...|...|.....:|||          :|         |.:.::.|....:.||
  Rat    29 NGGEKFEKNPHHWGADVRPEIKDD----------LY---------DPSYQDEEGPPPKLEY---- 70

  Fly   102 RWPDLGAQAFLHIGALYGLYQLFYANFYTFLWVVVTVWVSGIGITAGAHRLWSHKSYTASLPLRI 166
            .|.::...|.||||||||:..:.....||.|:..:...:|.:||||||||||||::|.|.||||:
  Rat    71 VWRNIILMALLHIGALYGITLVPSCKVYTCLFAYLYYVISALGITAGAHRLWSHRTYKARLPLRL 135

  Fly   167 LLAFAFSIAGQRDAYTWALDHRIHHKFSETDADPHNAKRGFFFAHVGWLFLTPHPKVVAKRKVID 231
            .|..|.::|.|.|.|.||.|||.|||||||.|||||::|||||:|||||.:..||.|..|...:|
  Rat   136 FLIIANTMAFQNDVYEWARDHRAHHKFSETHADPHNSRRGFFFSHVGWLLVRKHPAVKEKGGKLD 200

  Fly   232 MSDLEADAVCMFQRKYYIPLFALCSIILPVAVPWYFWNEDLWMSFWINFNMRFTWTLNVAFFVNS 296
            ||||:|:.:.||||:||.|...|...|||..||||.|.|....|..::..:|:...||..:.|||
  Rat   201 MSDLKAEKLVMFQRRYYKPGLLLMCFILPTLVPWYCWGETFVNSLCVSTFLRYAVVLNATWLVNS 265

  Fly   297 VAHMYGNKPYDKNLMSTEAPIVSLLAMGEGWHNYHHVFPWDYKTGEFGNYSLNITTGFIDFCAWL 361
            .||:||.:|||||:.|.|..:||:.|:|||:|||||.||:||...|: .:.:|.||.|||..|.|
  Rat   266 AAHLYGYRPYDKNISSRENILVSMGAVGEGFHNYHHAFPYDYSASEY-RWHINFTTFFIDCMALL 329

  Fly   362 GLAKGRKSVSPDMVLRRAKKCGD 384
            |||..||.||...||.|.|:.|:
  Rat   330 GLAYDRKRVSKAAVLARIKRTGE 352

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9743	NP_651781.1	Delta9-FADS-like	130..368	CDD:239582	126/237 (53%)
CG9743	NP_651781.1	FA_desaturase	131..335	CDD:278890	109/203 (54%)
Scd2	NP_114029.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	14..43		5/13 (38%)
		Delta9-FADS-like	99..336	CDD:239582	126/237 (53%)
		FA_desaturase	101..305	CDD:278890	110/203 (54%)
		Histidine box-1. /evidence=ECO:0000305	119..124		4/4 (100%)
		Histidine box-2. /evidence=ECO:0000305	156..160		2/3 (67%)
		Histidine box-3. /evidence=ECO:0000305	297..301		3/3 (100%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	55	1.000	Domainoid score	I10831
eggNOG	1	0.900	-	-		E1_COG1398
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG63267
OrthoDB	1	1.010	-	-		D296120at33208
OrthoFinder	1	1.000	-	-		FOG0000495
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11351
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X207
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.930