DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15531 and Scd2

DIOPT Version :9

Sequence 1:	NP_651780.1	Gene:	CG15531 / 43592	FlyBaseID:	FBgn0039755	Length:	334	Species:	Drosophila melanogaster
Sequence 2:	NP_114029.1	Gene:	Scd2 / 83792	RGDID:	621177	Length:	358	Species:	Rattus norvegicus

Alignment Length:	307	Identity:	96/307 - (31%)
Similarity:	155/307 - (50%)	Gaps:	27/307 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 DQSGDSIHKKRDAIWPLVLFYIHLNILGVYGIYVLLTSASWATILFTALLTLLGTLGVTVGVHRL 74
            |:.|..  .|.:.:|..::....|:|..:||| .|:.|....|.||..|..::..||:|.|.|||
  Rat    60 DEEGPP--PKLEYVWRNIILMALLHIGALYGI-TLVPSCKVYTCLFAYLYYVISALGITAGAHRL 121

  Fly    75 WAHRTFTASKPLKVFLMFCQTTAGQGSIYSVVQAHRLHHAKFQQDEDPYYSKHSFMYAQVRGGLL 139
            |:|||:.|..||::||:...|.|.|..:|...:.||.||...:...||:.|:..|.::.|...|:
  Rat   122 WSHRTYKARLPLRLFLIIANTMAFQNDVYEWARDHRAHHKFSETHADPHNSRRGFFFSHVGWLLV 186

  Fly   140 KYSPQQEELLKDVDMSDLESDPVVMFQKRFY---VLLYIFLNVLLSVNTPFQYFGDSLATSMFVG 201
            :..|..:|....:|||||:::.:||||:|:|   :||..|   :|....|:..:|::...|:.|.
  Rat   187 RKHPAVKEKGGKLDMSDLKAEKLVMFQRRYYKPGLLLMCF---ILPTLVPWYCWGETFVNSLCVS 248

  Fly   202 FWLRSLIVINLGNLVHSSHFIWSIHKGFKPTDSN---------SIFLITKSYWPQYHYLLPRDYQ 257
            .:||..:|:|...||:|:..::    |::|.|.|         |:..:.:.: ..||:..|.||.
  Rat   249 TFLRYAVVLNATWLVNSAAHLY----GYRPYDKNISSRENILVSMGAVGEGF-HNYHHAFPYDYS 308

  Fly   258 SGEYGNYASGIGSSMIRVFAALDWAKDLKTIGSVAVRQGLTKAVETG 304
            :.|| .:.....:..|...|.|..|.|.|.:...||   |.:...||
  Rat   309 ASEY-RWHINFTTFFIDCMALLGLAYDRKRVSKAAV---LARIKRTG 351

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15531	NP_651780.1	Delta9-FADS-like	49..286	CDD:239582	79/248 (32%)
Scd2	NP_114029.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	14..43
		Delta9-FADS-like	99..336	CDD:239582	79/245 (32%)
		FA_desaturase	101..305	CDD:278890	68/211 (32%)
		Histidine box-1. /evidence=ECO:0000305	119..124		4/4 (100%)
		Histidine box-2. /evidence=ECO:0000305	156..160		2/3 (67%)
		Histidine box-3. /evidence=ECO:0000305	297..301		1/3 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1398
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D971318at2759
OrthoFinder	1	1.000	-	-		FOG0000495
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11351
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X207
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.920