DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15531 and Scd4

DIOPT Version :9

Sequence 1:	NP_651780.1	Gene:	CG15531 / 43592	FlyBaseID:	FBgn0039755	Length:	334	Species:	Drosophila melanogaster
Sequence 2:	NP_899039.2	Gene:	Scd4 / 329065	MGIID:	2670997	Length:	353	Species:	Mus musculus

Alignment Length:	303	Identity:	92/303 - (30%)
Similarity:	153/303 - (50%)	Gaps:	19/303 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 DQSGDSIHKKRDAIWPLVLFYIHLNILGVYGIYVLLTSASWATILFTALLTLLGTLGVTVGVHRL 74
            |:.|..  .|.:.:|..::|...|::..:||| .|:.|....|.|......::..||:|.|.|||
Mouse    55 DEEGPP--PKLEYVWRNIIFMALLHVGALYGI-TLVPSCKVYTWLLGVFYNVVAGLGITAGAHRL 116

  Fly    75 WAHRTFTASKPLKVFLMFCQTTAGQGSIYSVVQAHRLHHAKFQQDEDPYYSKHSFMYAQVRGGLL 139
            |:|||:.|..||::||:...|.|.|..:|...:.||.||...:...||:.|:..|.::.|...|:
Mouse   117 WSHRTYKARLPLRIFLIMANTMAFQNDVYEWARDHRAHHKFSETHADPHNSRRGFFFSHVGWLLV 181

  Fly   140 KYSPQQEELLKDVDMSDLESDPVVMFQKRFYVLLYIFLNVLLSVNTPFQYFGDSLATSMFVGFWL 204
            :..|..:|..|::|||||:::.:||||:|:|.|....:.::|....|:..:|::...|:.|..:|
Mouse   182 RKHPAVKEKGKNLDMSDLKAEKLVMFQRRYYKLAVTLMFIILPTLVPWYLWGETFQHSLCVSNFL 246

  Fly   205 RSLIVINLGNLVHSSHFIWSIHKGFKPTD-----SNSIFLITKSY---WPQYHYLLPRDYQSGEY 261
            |..:::|...||:|:..::    |::|.|     ..:.|:...|.   :..||:..|.||...||
Mouse   247 RYAVLLNFTWLVNSAAHLY----GYRPYDRGIGARENPFVSMASLGEGFHNYHHTFPYDYSVSEY 307

  Fly   262 GNYASGIGSSMIRVFAALDWAKDLKTIGSVAVRQGLTKAVETG 304
             .:.....:..|...|||..|.|.|.:....|   |.:...||
Mouse   308 -RWHINFTTFFIDCMAALGLAYDRKKVSKAVV---LARIKRTG 346

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15531	NP_651780.1	Delta9-FADS-like	49..286	CDD:239582	76/244 (31%)
Scd4	NP_899039.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..42
		Delta9-FADS-like	94..331	CDD:239582	76/241 (32%)
		FA_desaturase	94..300	CDD:278890	65/209 (31%)
		Histidine box-1. /evidence=ECO:0000305	114..119		4/4 (100%)
		Histidine box-2. /evidence=ECO:0000305	151..155		2/3 (67%)
		Histidine box-3. /evidence=ECO:0000305	292..296		1/3 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1398
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D971318at2759
OrthoFinder	1	1.000	-	-		FOG0000495
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11351
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X207
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	7	6.880