DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9747 and Scd4

DIOPT Version :9

Sequence 1:	NP_001287604.1	Gene:	CG9747 / 43591	FlyBaseID:	FBgn0039754	Length:	461	Species:	Drosophila melanogaster
Sequence 2:	NP_899039.2	Gene:	Scd4 / 329065	MGIID:	2670997	Length:	353	Species:	Mus musculus

Alignment Length:	358	Identity:	153/358 - (42%)
Similarity:	213/358 - (59%)	Gaps:	31/358 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 RRGEDSSPELPPRGKLQLPPKREELPRSVVPKEIANHVPKDAIDLEEYTRTFVGDRVLGWQFQAP 106
            ||.:|...::|    ||....|.|:              ||  ||  |..::..:.  |...:..
Mouse    24 RRQQDGEEKMP----LQAEDIRPEI--------------KD--DL--YDPSYQDEE--GPPPKLE 64

  Fly   107 LKWDKVIQISLLHIVA--GICLLTYPLRELNPYTTIWSFFVGGVAGFGVTAGAHRFWTHKSYKAN 169
            ..|..:|.::|||:.|  ||.|:.    ....||.:...|...|||.|:||||||.|:|::|||.
Mouse    65 YVWRNIIFMALLHVGALYGITLVP----SCKVYTWLLGVFYNVVAGLGITAGAHRLWSHRTYKAR 125

  Fly   170 TVLRSILMVCYCVAGQNTLYDWVRDHRVHHKYSETDADPHNANRGFFFSHVGWLMMLKHPEVLRR 234
            ..||..|::...:|.||.:|:|.||||.|||:|||.|||||:.|||||||||||::.|||.|..:
Mouse   126 LPLRIFLIMANTMAFQNDVYEWARDHRAHHKFSETHADPHNSRRGFFFSHVGWLLVRKHPAVKEK 190

  Fly   235 GRQIDMSDILADPVVRFHQKYFIPLKTFFCFILPTVIPVYCWGETWTLAFIQQCLFRYVSSLNFT 299
            |:.:||||:.|:.:|.|.::|:....|....||||::|.|.||||:..:.......||...||||
Mouse   191 GKNLDMSDLKAEKLVMFQRRYYKLAVTLMFIILPTLVPWYLWGETFQHSLCVSNFLRYAVLLNFT 255

  Fly   300 WSVNSAAHLWGSRPYDKRIMPSENIYVSLLAMGEGWHNYHHVFPWDYKAAELGNYTVNFTTMVLD 364
            |.|||||||:|.||||:.|...||.:||:.::|||:|||||.||:||..:|. .:.:||||..:|
Mouse   256 WLVNSAAHLYGYRPYDRGIGARENPFVSMASLGEGFHNYHHTFPYDYSVSEY-RWHINFTTFFID 319

  Fly   365 AFHKLGWAWNMKQPSKELVRRTLEKYGDGTHAS 397
            ....||.|::.|:.||.:|...:::.|||:|.|
Mouse   320 CMAALGLAYDRKKVSKAVVLARIKRTGDGSHKS 352

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9747	NP_001287604.1	Delta9-FADS-like	135..376	CDD:239582	121/240 (50%)
CG9747	NP_001287604.1	FA_desaturase	140..343	CDD:278890	106/202 (52%)
Scd4	NP_899039.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..42		6/21 (29%)
		Delta9-FADS-like	94..331	CDD:239582	120/237 (51%)
		FA_desaturase	94..300	CDD:278890	108/205 (53%)
		Histidine box-1. /evidence=ECO:0000305	114..119		3/4 (75%)
		Histidine box-2. /evidence=ECO:0000305	151..155		2/3 (67%)
		Histidine box-3. /evidence=ECO:0000305	292..296		3/3 (100%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	56	1.000	Domainoid score	I10942
eggNOG	1	0.900	-	-		E1_COG1398
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG63267
OrthoDB	1	1.010	-	-		D296120at33208
OrthoFinder	1	1.000	-	-		FOG0000495
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11351
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X207
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.930