DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9747 and Scd3

DIOPT Version :9

Sequence 1:	NP_001287604.1	Gene:	CG9747 / 43591	FlyBaseID:	FBgn0039754	Length:	461	Species:	Drosophila melanogaster
Sequence 2:	NP_077770.1	Gene:	Scd3 / 30049	MGIID:	1353437	Length:	359	Species:	Mus musculus

Alignment Length:	356	Identity:	160/356 - (44%)
Similarity:	220/356 - (61%)	Gaps:	30/356 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 PPRGKLQLPPKREELPRSVVPKEIANHVPKDAIDLEEYTRTFVGDRVLGWQFQ----APLK---- 108
            ||.|.||  ..||::  ..||           :.|||..|..:.:.:....:|    .|.|
Mouse    23 PPSGSLQ--NGREKV--KTVP-----------LYLEEDIRPEMKEDIYDPTYQDEEGPPPKLEYV 72

  Fly   109 WDKVIQISLLHIVA--GICLLTYPLRELNPYTTIWSFFVGGVAGFGVTAGAHRFWTHKSYKANTV 171
            |..:|.::|||:.|  ||.|:  |..:|  ||.:::|....::..|:.||.||.|:|::|||...
Mouse    73 WRNIILMALLHVGALYGITLV--PSCKL--YTCLFAFVYYVISIEGIGAGVHRLWSHRTYKARLP 133

  Fly   172 LRSILMVCYCVAGQNTLYDWVRDHRVHHKYSETDADPHNANRGFFFSHVGWLMMLKHPEVLRRGR 236
            ||..|::...:|.||.:|:|.||||.|||:|||.|||||:.|||||||||||::.|||.|..:|.
Mouse   134 LRIFLIIANTMAFQNDVYEWARDHRAHHKFSETHADPHNSRRGFFFSHVGWLLVRKHPAVKEKGG 198

  Fly   237 QIDMSDILADPVVRFHQKYFIPLKTFFCFILPTVIPVYCWGETWTLAFIQQCLFRYVSSLNFTWS 301
            ::||||:.|:.:|.|.::|:.|.....||||||::|.||||||:..:|....|.||...||.||.
Mouse   199 KLDMSDLKAEKLVMFQRRYYKPGILLMCFILPTLVPWYCWGETFLNSFYVATLLRYAVVLNATWL 263

  Fly   302 VNSAAHLWGSRPYDKRIMPSENIYVSLLAMGEGWHNYHHVFPWDYKAAELGNYTVNFTTMVLDAF 366
            |||||||:|.|||||.|.|.:|..|||.:||||:|||||.||:||.|:|. .:.:||||..:|..
Mouse   264 VNSAAHLYGYRPYDKNIDPRQNALVSLGSMGEGFHNYHHAFPYDYSASEY-RWHINFTTFFIDCM 327

  Fly   367 HKLGWAWNMKQPSKELVRRTLEKYGDGTHAS 397
            ..||.|::.|:.||..|...:::.|||:|.|
Mouse   328 AALGLAYDRKRVSKATVLARIKRTGDGSHKS 358

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9747	NP_001287604.1	Delta9-FADS-like	135..376	CDD:239582	124/240 (52%)
CG9747	NP_001287604.1	FA_desaturase	140..343	CDD:278890	108/202 (53%)
Scd3	NP_077770.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..34		6/12 (50%)
		Delta9-FADS-like	97..337	CDD:239582	125/242 (52%)
		FA_desaturase	102..306	CDD:278890	109/203 (54%)
		Histidine box-1. /evidence=ECO:0000305	120..125		3/4 (75%)
		Histidine box-2. /evidence=ECO:0000305	157..161		2/3 (67%)
		Histidine box-3. /evidence=ECO:0000305	298..302		3/3 (100%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	56	1.000	Domainoid score	I10942
eggNOG	1	0.900	-	-		E1_COG1398
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG63267
OrthoDB	1	1.010	-	-		D296120at33208
OrthoFinder	1	1.000	-	-		FOG0000495
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11351
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X207
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.930