DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9747 and Scd2

DIOPT Version :9

Sequence 1:	NP_001287604.1	Gene:	CG9747 / 43591	FlyBaseID:	FBgn0039754	Length:	461	Species:	Drosophila melanogaster
Sequence 2:	NP_033154.2	Gene:	Scd2 / 20250	MGIID:	98240	Length:	358	Species:	Mus musculus

Alignment Length:	288	Identity:	139/288 - (48%)
Similarity:	195/288 - (67%)	Gaps:	7/288 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly   109 WDKVIQISLLHIVA--GICLLTYPLRELNPYTTIWSFFVGGVAGFGVTAGAHRFWTHKSYKANTV 171
            |..:|.::|||:.|  ||.|:  |..:|  ||.::::....::..|:||||||.|:|::|||...
Mouse    72 WRNIILMALLHLGALYGITLV--PSCKL--YTCLFAYLYYVISALGITAGAHRLWSHRTYKARLP 132

  Fly   172 LRSILMVCYCVAGQNTLYDWVRDHRVHHKYSETDADPHNANRGFFFSHVGWLMMLKHPEVLRRGR 236
            ||..|::...:|.||.:|:|.||||.|||:|||.|||||:.|||||||||||::.|||.|..:|.
Mouse   133 LRLFLIIANTMAFQNDVYEWARDHRAHHKFSETHADPHNSRRGFFFSHVGWLLVRKHPAVKEKGG 197

  Fly   237 QIDMSDILADPVVRFHQKYFIPLKTFFCFILPTVIPVYCWGETWTLAFIQQCLFRYVSSLNFTWS 301
            ::||||:.|:.:|.|.::|:.|.....||:|||::|.||||||:..:.......||...||.||.
Mouse   198 KLDMSDLKAEKLVMFQRRYYKPGLLLMCFVLPTLVPWYCWGETFVNSLCVSTFLRYAVVLNATWL 262

  Fly   302 VNSAAHLWGSRPYDKRIMPSENIYVSLLAMGEGWHNYHHVFPWDYKAAELGNYTVNFTTMVLDAF 366
            |||||||:|.|||||.|...|||.||:.|:|||:|||||.||:||.|:|. .:.:||||..:|..
Mouse   263 VNSAAHLYGYRPYDKNISSRENILVSMGAVGEGFHNYHHAFPYDYSASEY-RWHINFTTFFIDCM 326

  Fly   367 HKLGWAWNMKQPSKELVRRTLEKYGDGT 394
            ..||.|::.|:.|:..|...:::.|||:
Mouse   327 ALLGLAYDRKRVSRAAVLARIKRTGDGS 354

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9747	NP_001287604.1	Delta9-FADS-like	135..376	CDD:239582	122/240 (51%)
CG9747	NP_001287604.1	FA_desaturase	140..343	CDD:278890	106/202 (52%)
Scd2	NP_033154.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	16..39
		Delta9-FADS-like	96..336	CDD:239582	123/242 (51%)
		FA_desaturase	101..305	CDD:278890	107/203 (53%)
		Histidine box-1. /evidence=ECO:0000305	119..124		3/4 (75%)
		Histidine box-2. /evidence=ECO:0000305	156..160		2/3 (67%)
		Histidine box-3. /evidence=ECO:0000305	297..301		3/3 (100%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	56	1.000	Domainoid score	I10942
eggNOG	1	0.900	-	-		E1_COG1398
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG63267
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000495
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11351
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X207
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.920