Protein Alignment Mlc2 and MYL10

DIOPT Version :9

• Sequence 1: NP_524586.1
• Gene: Mlc2 / 43587
• FlyBaseID: FBgn0002773
• Length: 222
• Species: Drosophila melanogaster
• Sequence 2: NP_612412.2
• Gene: MYL10 / 93408
• HGNCID: 29825
• Length: 226
• Species: Homo sapiens
• Alignment Length: 223
• Identity: 72/223 - (32%)
• Similarity: 102/223 - (45%)
• Gaps: 50/223 - (22%)

  Fly    33 PAPAATPAPAASATGSKRASGGSRGSRKSKRAGSSVFSVFSQKQIAEFKE--------------- 82
            |.|.......|.....|||.|         .|.|:|||:|.|.||.||||
Human    17 PRPPKVLGLQAPRRARKRAEG---------TASSNVFSMFDQSQIQEFKESLALSPRLERNGMIS 72

  Fly    83 -------------------AFQLMDADKDGIIGKNDLRAAFDSVGKI-ANDKELDAMLGEASGPI 127
                               ||.:||.::||.|.|.|||..|.::|:| ..::||:||:.||.|||
Human    73 AHCNLCLTGSSNSPASASQAFTIMDQNRDGFIDKEDLRDTFAALGRINVKNEELEAMVKEAPGPI 137

  Fly   128 NFTQLLTLFANRMATSGANDEDEVVIAAFKTFDND--GLIDGDKFREMLMNFGDKFTMKEVDDAY 190
            |||..||:|..::.   ..|.:|.::.|||.||.:  |.:..|..:|.||...|:|:.:||...:
Human   138 NFTVFLTMFGEKLK---GTDPEETILHAFKVFDTEGKGFVKADVIKEKLMTQADRFSEEEVKQMF 199

  Fly   191 DQMVIDDKNQIDTAALIEMLTGKGEEEE 218
            .....|....:|...|..::| .|||::
Human   200 AAFPPDVCGNLDYRNLCYVIT-HGEEKD 226

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mlc2	NP_524586.1	PTZ00184	73..213	CDD:185504	56/176 (32%)
MYL10	NP_612412.2	FRQ1	40..223	CDD:227455	61/186 (33%)
		EF-hand motif	89..118	CDD:320054	12/28 (43%)
		EF-hand motif	149..187	CDD:320054	12/40 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0031
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1435392at2759
OrthoFinder	1	1.000	-	-		FOG0000218
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23049
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.920