Protein Alignment Mlc2 and MYL7

DIOPT Version :9

• Sequence 1: NP_524586.1
• Gene: Mlc2 / 43587
• FlyBaseID: FBgn0002773
• Length: 222
• Species: Drosophila melanogaster
• Sequence 2: XP_011513765.1
• Gene: MYL7 / 58498
• HGNCID: 21719
• Length: 231
• Species: Homo sapiens
• Alignment Length: 235
• Identity: 74/235 - (31%)
• Similarity: 116/235 - (49%)
• Gaps: 69/235 - (29%)

  Fly    48 SKRASGGSRG----SRKSKRAGSSVFSVFSQKQIAEFKE-----------------------AFQ 85
            |::|  |:||    :::::|..|:|||:|.|.||.||||                       ||.
Human     3 SRKA--GTRGKVAATKQAQRGSSNVFSMFEQAQIQEFKEVSPPPPTFPRAGGCSHLKAPIPQAFS 65

  Fly    86 LMDADKDGIIGKNDLRAAFDSVGKIA-NDKELDAMLGEASGPINFTQLLTLFANRMATSGANDED 149
            .:|.::||||.|.|||..:..:||:: .::||||||.|..||||||..||||..::   ...|.:
Human    66 CIDQNRDGIICKADLRETYSQLGKVSVPEEELDAMLQEGKGPINFTVFLTLFGEKL---NGTDPE 127

  Fly   150 EVVIAAFKTFD--NDGLIDGDKFREMLMNFGDKF-----------------------------TM 183
            |.:::||:.||  ..|:::.|:|:::|:...|||                             |.
Human   128 EAILSAFRMFDPSGKGVVNKDEFKQLLLTQADKFSPAEVRLPSPFNTHPQHLLWAFTHDPEPSTS 192

  Fly   184 KEVDDAYDQMV----IDDKNQIDTAALIEMLTGKGEEEEE 219
            :.|....:||.    :|....||..:|..::| .|:|:||
Human   193 EAVAGRVEQMFALTPMDLAGNIDYKSLCYIIT-HGDEKEE 231

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mlc2	NP_524586.1	PTZ00184	73..213	CDD:185504	59/198 (30%)
MYL7	XP_011513765.1	EF-hand_7	62..154	CDD:290234	39/94 (41%)
		EF-hand_8	72..157	CDD:290545	37/87 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0031
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1435392at2759
OrthoFinder	1	1.000	-	-		FOG0000218
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23049
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.920