Protein Alignment Mlc2 and MYL5

DIOPT Version :9

• Sequence 1: NP_524586.1
• Gene: Mlc2 / 43587
• FlyBaseID: FBgn0002773
• Length: 222
• Species: Drosophila melanogaster
• Sequence 2: XP_006713949.1
• Gene: MYL5 / 4636
• HGNCID: 7586
• Length: 328
• Species: Homo sapiens
• Alignment Length: 221
• Identity: 89/221 - (40%)
• Similarity: 121/221 - (54%)
• Gaps: 19/221 - (8%)

  Fly    14 KEEGGT--SETASEAASEAATP---APAATPAPAASATGSKRASGGSR-------GSRKSKRAGS 66
            :..||.  ...|:||...|:.|   .|...|....|:...:|....||       |:.:::||.|
Human   112 RRAGGPLFPRAAAEAPPSASWPCVHTPDCGPGRTLSSCAERRRPEASRKTKKKEGGALRAQRASS 176

  Fly    67 SVFSVFSQKQIAEFKEAFQLMDADKDGIIGKNDLRAAFDSVGKI-ANDKELDAMLGEASGPINFT 130
            :|||.|.|.||.||||||.|||.::||.|.|.||:..:.|:||. ..|.||||||.|||||||||
Human   177 NVFSNFEQTQIQEFKEAFTLMDQNRDGFIDKEDLKDTYASLGKTNVKDDELDAMLKEASGPINFT 241

  Fly   131 QLLTLFANRMATSGANDEDEVVIAAFKTFDND--GLIDGDKFREMLMNFGDKFTMKEVDDAYDQM 193
            ..|.||..:::   ..|.:|.::.|||..|.|  |.|:.:..:.:||:..||.|.:|||..:...
Human   242 MFLNLFGEKLS---GTDAEETILNAFKMLDPDGKGKINKEYIKRLLMSQADKMTAEEVDQMFQFA 303

  Fly   194 VIDDKNQIDTAALIEMLTGKGEEEEE 219
            .||....:|..||..::| .|||:||
Human   304 SIDVAGNLDYKALSYVIT-HGEEKEE 328

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mlc2	NP_524586.1	PTZ00184	73..213	CDD:185504	63/142 (44%)
MYL5	XP_006713949.1	FRQ1	170..314	CDD:227455	67/146 (46%)
		EFh	189..247	CDD:238008	35/57 (61%)
		EFh	263..314	CDD:238008	18/50 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0031
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1435392at2759
OrthoFinder	1	1.000	-	-		FOG0000218
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23049
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.920