DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mlc2 and myl9a

DIOPT Version :9

Sequence 1:	NP_524586.1	Gene:	Mlc2 / 43587	FlyBaseID:	FBgn0002773	Length:	222	Species:	Drosophila melanogaster
Sequence 2:	NP_001006027.1	Gene:	myl9a / 450006	ZFINID:	ZDB-GENE-041010-120	Length:	174	Species:	Danio rerio

Alignment Length:	176	Identity:	67/176 - (38%)
Similarity:	104/176 - (59%)	Gaps:	6/176 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 TGSKRASGGSRGSRKSKRAGSSVFSVFSQKQIAEFKEAFQLMDADKDGIIGKNDLRAAFDSVGKI 110
            :.:|||.|.:. .::.:||.|:||::|.|.||.||||||.::|.::||.|.|.||.....|:||.
Zfish     2 SAAKRAKGKTT-RKRPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASLGKN 65

  Fly   111 ANDKELDAMLGEASGPINFTQLLTLFANRMATSGANDEDEVVIAAFKTFDND--GLIDGDKFREM 173
            .:|:.|:.|:.||.||||||..||:|..|:   ...|.::|:..||..||.|  |.|..|..|::
Zfish    66 PSDEYLEGMMSEAPGPINFTMFLTMFGERL---NGTDPEDVIRNAFTCFDEDATGFIHEDHLRDL 127

  Fly   174 LMNFGDKFTMKEVDDAYDQMVIDDKNQIDTAALIEMLTGKGEEEEE 219
            |...||:||.:|||:.:.:..||.|...:......:|....:::::
Zfish   128 LTTMGDRFTDEEVDELFREAPIDKKGNFNYVEFTRILKHGAKDKDD 173

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mlc2	NP_524586.1	PTZ00184	73..213	CDD:185504	57/141 (40%)
myl9a	NP_001006027.1	FRQ1	20..170	CDD:227455	61/152 (40%)
		EFh	34..>78	CDD:238008	19/43 (44%)
		EFh	104..165	CDD:298682	20/60 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1435392at2759
OrthoFinder	1	1.000	-	-		FOG0000218
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23049
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	4.020