DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mlc2 and myl7

DIOPT Version :9

Sequence 1:	NP_524586.1	Gene:	Mlc2 / 43587	FlyBaseID:	FBgn0002773	Length:	222	Species:	Drosophila melanogaster
Sequence 2:	NP_571404.1	Gene:	myl7 / 30592	ZFINID:	ZDB-GENE-991019-3	Length:	172	Species:	Danio rerio

Alignment Length:	175	Identity:	76/175 - (43%)
Similarity:	115/175 - (65%)	Gaps:	9/175 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 SKRASGGSRGSRKSKRAGSSVFSVFSQKQIAEFKEAFQLMDADKDGIIGKNDLRAAFDSVGKI-A 111
            ||:|: ..|| :.::|..|:|||:|.|.||.||||||..:|.::||:|.|:||:..:..:||: .
Zfish     3 SKKAA-AKRG-KTAQRGSSNVFSMFEQSQIQEFKEAFGCIDQNRDGVINKSDLKETYAQLGKLNV 65

  Fly   112 NDKELDAMLGEASGPINFTQLLTLFANRMATSGANDEDEVVIAAFKTFDND--GLIDGDKFREML 174
            :|:||::||.|..||||||..||||..::   ...|.:|.::||||.||.:  |:::.|:|:.:|
Zfish    66 SDEELESMLTEGKGPINFTVFLTLFGEKL---NGTDPEETILAAFKLFDPNATGVVNKDEFKRLL 127

  Fly   175 MNFGDKFTMKEVDDAYDQMVIDDKNQIDTAALIEMLTGKGEEEEE 219
            |...||||.:|||.|:....||....||..:|..::| .|:|:||
Zfish   128 MTQADKFTAEEVDQAFAVAPIDVAGNIDYKSLCYIIT-HGDEKEE 171

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mlc2	NP_524586.1	PTZ00184	73..213	CDD:185504	61/142 (43%)
myl7	NP_571404.1	FRQ1	18..165	CDD:227455	66/150 (44%)
		EFh	32..128	CDD:298682	42/98 (43%)
		EFh	103..164	CDD:298682	24/60 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0031
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1435392at2759
OrthoFinder	1	1.000	-	-		FOG0000218
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23049
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.920