DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mlc2 and mlc-1

DIOPT Version :9

Sequence 1:	NP_524586.1	Gene:	Mlc2 / 43587	FlyBaseID:	FBgn0002773	Length:	222	Species:	Drosophila melanogaster
Sequence 2:	NP_510829.2	Gene:	mlc-1 / 181776	WormBaseID:	WBGene00003369	Length:	170	Species:	Caenorhabditis elegans

Alignment Length:	169	Identity:	67/169 - (39%)
Similarity:	95/169 - (56%)	Gaps:	10/169 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 SRGSRK---SKRAGSSVFSVFSQKQIAEFKEAFQLMDADKDGIIGKNDLRAAFDSVGKIANDKEL 116
            |:.::|   .||:||.. :.|.||.|.||||||.:||.:|||||.|:||:..:.|:|:||.|.::
Worm     2 SKAAKKKSSKKRSGSEA-AQFDQKTIQEFKEAFGIMDQNKDGIIDKSDLKDLYASMGQIAPDSQI 65

  Fly   117 DAMLGEASGPINFTQLLTLFANRMATSGANDEDEVVIAAFKTFDND--GLIDGDKFREMLMN-FG 178
            |||:.|||||||||..||||..|:.   ..|.:..:|.||..||..  |.|..|...::|.| .|
Worm    66 DAMIKEASGPINFTVFLTLFGERLT---GTDPEATIIGAFAMFDKKDCGKIKEDDLIKILQNKRG 127

  Fly   179 DKFTMKEVDDAYDQMVIDDKNQIDTAALIEMLTGKGEEE 217
            :.....||...|......:..::|..|...::|...::|
Worm   128 EPLDEDEVKAMYKGKPPIEGGEVDYKAFAHLITTGAQDE 166

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mlc2	NP_524586.1	PTZ00184	73..213	CDD:185504	59/142 (42%)
mlc-1	NP_510829.2	FRQ1	13..159	CDD:227455	62/149 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0031
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1435392at2759
OrthoFinder	1	1.000	-	-		FOG0000218
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23049
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.880