Protein Alignment Mlc2 and CETN2

DIOPT Version :10

• Sequence 1: NP_524586.1
• Gene: Mlc2 / 43587
• FlyBaseID: FBgn0002773
• Length: 222
• Species: Drosophila melanogaster
• Sequence 2: NP_004335.1
• Gene: CETN2 / 1069
• HGNCID: 1867
• Length: 172
• Species: Homo sapiens
• Alignment Length: 182
• Identity: 50/182 - (27%)
• Similarity: 80/182 - (43%)
• Gaps: 28/182 - (15%)

  Fly    45 ATGSKRASGGSRGSRKSKRAGSSVFSVFSQKQIAEFKEAFQLMDADKDGIIGKNDLRAAFDSVGK 109
            |:..|:|:..|...||.    .|.....:::|..|.:|||.|.|||..|.|...:|:.|..::|.
Human     2 ASNFKKANMASSSQRKR----MSPKPELTEEQKQEIREAFDLFDADGTGTIDVKELKVAMRALGF 62

  Fly   110 IANDKELDAMLG----EASGPINFTQLLTLFANRMATSGANDEDEVVIAAFKTFDND--GLIDGD 168
            ....:|:..|:.    |.:|.:||...||:...:|:   ..|..|.::.|||.||:|  |.|...
Human    63 EPKKEEIKKMISEIDKEGTGKMNFGDFLTVMTQKMS---EKDTKEEILKAFKLFDDDETGKISFK 124

  Fly   169 KFREMLMNFGDKFTMKEVDDAYDQMVIDDKNQIDTAALIEMLTGKGEEEEEE 220
            ..:.:....|:..|.:|:.:..|:...|               |.||..|:|
Human   125 NLKRVAKELGENLTDEELQEMIDEADRD---------------GDGEVSEQE 161

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mlc2	NP_524586.1	PTZ00184	73..213	CDD:185504	38/145 (26%)
CETN2	NP_004335.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..30		7/31 (23%)
		Required for self-assembly	2..25		7/26 (27%)
		PTZ00183	16..172	CDD:185503	46/168 (27%)