Protein Alignment CG11498 and F49E10.4

DIOPT Version :10

• Sequence 1: NP_001334706.1
• Gene: CG11498 / 43585
• FlyBaseID: FBgn0039749
• Length: 571
• Species: Drosophila melanogaster
• Sequence 2: NP_001360757.1
• Gene: F49E10.4 / 186045
• WormBaseID: WBGene00018641
• Length: 612
• Species: Caenorhabditis elegans
• Alignment Length: 587
• Identity: 134/587 - (22%)
• Similarity: 240/587 - (40%)
• Gaps: 131/587 - (22%)

  Fly    91 SVLRSVIAELPLDLLLEHLPHSAYLLESFFTR--LTTLN---TTPKPDVPSETVAWQLV--RLFA 148
            |||.:::.  |::.|:..:|::..|||:.:.:  |.|:.   ..|..::..|.:..|||  ..|.
 Worm    51 SVLFNILP--PVEQLVSEIPYTLPLLEAIYLKCELRTVEDGLILPTKELCCEQLFCQLVWWTAFC 113

  Fly   149 NPHESGLRQRC----------TRLLQALAQYEPGLRQTLRERRRSFDNAVQGLGVHGLTTDASGQ 203
            ....|.|::.|          ..|:..:.:..|.|.:..||.|......::.||.|||...:||
 Worm   114 EQSNSSLKKHCAMFAEFQPCIATLMSIVGRQCPDLVKRAREDRNQLKTCLESLGCHGLVNCSSG- 177

  Fly   204 LISLHVALKTELQRHVDTYKMAIHKLEELSMVTVNQ--DPAHSSHQRLLAINYGDIQQRLIDNKT 266
            ||.:..|:..||.:||:..|:...:::||.....:.  ||:..||||.:::....:.:||..|:|
 Worm   178 LIRMTDAVHLELLKHVENLKIICSQIKELQHDPKSNAPDPSCESHQRQMSMRLSQVFERLKLNET 242

  Fly   267 LLTMLDKPALKQ-LQTLVENLSTRVENDKEVLTCVGQVRRLDAQ--ALVEKRP-AAGLLMNFSRG 327
            |..:|::....| |.:|:.....||.:||.::.......|...:  ||.:..| .|.|::.|:..
 Worm   243 LQCVLEETFQNQHLGSLLRICRKRVGSDKLLIGLFNAFARAAPEDFALQQMDPIVAQLIVVFNNS 307

  Fly   328 CEVVLHMMGPEGGPPGSSHSIGKTTPPGGASTSSCSDGYHS------------------------ 368
            ...:|.|. |:        .:..|....|:||||.|.|..|
 Worm   308 YNKLLQMC-PD--------DVSSTRLSSGSSTSSVSQGASSINEKFSVRPSENSIQFDSLKQEIS 363

  Fly   369 ---------------------DDS----------------------GSDDSSEMVSLYRNLYVEN 390
                                 :||                      ..:.:|::|:.:..|::..
 Worm   364 KLRKELRVANYTITQLREKSEEDSVIKESSLPLPDYPDATAYYNSATKEQTSQLVTRFGELFIFA 428

  Fly   391 RADALEALDSLPQIKHAHSLKGKILFSMIVLSFRLCHGMRERKVLEVRRVL---NCPLDSSSETT 452
            ..:..::||:||:::....|:.......::|::.:.....|.:.|.|.:.|   |.....|:|.|
 Worm   429 SNELRDSLDTLPEMEGEDDLQAIFGHETLILTYNVVKEHIEDRKLAVLKALGSVNNNAKESNELT 493

  Fly   453 LSLDRSVRQHLFETAESFPL----------GEIERSVFNQVLSTLHEYPCLESCPPLTHYVSACV 507
                      :||.|.|..|          |.|...:..||...|.|||.:|.|..:..|:..|:
 Worm   494 ----------MFEDALSSQLHKEFTTTKAGGHIAEDLCQQVFKKLDEYPGVEECLTIHQYIQKCI 548

  Fly   508 RLAWRMINQKAP-YYLDMDFNLGFLRPEKHERHPQADRRSDLIKAFLWPALM--QNNQCAFKAVV 569
            .::|.:  |..| ..|.::::.....|.:|.|...:...:.::. |:||||:  .:|:...||:|
 Worm   549 SISWDI--QCCPERKLKLEYDGAEFEPSRHSRGAYSGTTNQVVN-FIWPALIDTSDNRVLLKAIV 610

  Fly   570 AT 571
            .|
 Worm   611 LT 612

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11498	NP_001334706.1	MIEAP	378..571	CDD:464982	49/208 (24%)
F49E10.4	NP_001360757.1	MIEAP	415..612	CDD:464982	50/209 (24%)