DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15529 and CLNK

DIOPT Version :9

Sequence 1:	NP_001303487.1	Gene:	CG15529 / 43584	FlyBaseID:	FBgn0039748	Length:	196	Species:	Drosophila melanogaster
Sequence 2:	XP_011512077.1	Gene:	CLNK / 116449	HGNCID:	17438	Length:	443	Species:	Homo sapiens

Alignment Length:	140	Identity:	33/140 - (23%)
Similarity:	62/140 - (44%)	Gaps:	22/140 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 PQQQPREDYVIVDDADVNYAEIEERHVEKEQYYFTVDRPTAERMLHGREDGSCLVRPFKAADQWI 124
            |::..|:|   |...:....|...:.||             |..:...:|||.|||......:..
Human   311 PKRSDRKD---VQHNEWYIGEYSRQAVE-------------EAFMKENKDGSFLVRDCSTKSKEE 359

  Fly   125 RYIVSIWAADQYYHLFIRQVDRRQRYAIGQKKSQERCFGSPSEIVEFYTEHPLLC------TNKV 183
            .|:::::..::.|::.||.::|.|::|:|.....:..|.|..:|:|.|...|::.      |...
Human   360 PYVLAVFYENKVYNVKIRFLERNQQFALGTGLRGDEKFDSVEDIIEHYKNFPIILIDGKDKTGVH 424

  Fly   184 RSQCVQLRPI 193
            |.||...:|:
Human   425 RKQCHLTQPL 434

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15529	NP_001303487.1	SH2	82..188	CDD:301589	26/111 (23%)
CLNK	XP_011512077.1	SH2_BLNK_SLP-76	312..432	CDD:198183	31/135 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	50	1.000	Domainoid score	I11671
eggNOG	1	0.900	-	-		E1_28NC9
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810