Protein Alignment AdoR and GALR2

DIOPT Version :9

• Sequence 1: NP_651772.1
• Gene: AdoR / 43583
• FlyBaseID: FBgn0039747
• Length: 774
• Species: Drosophila melanogaster
• Sequence 2: NP_003848.1
• Gene: GALR2 / 8811
• HGNCID: 4133
• Length: 387
• Species: Homo sapiens
• Alignment Length: 361
• Identity: 87/361 - (24%)
• Similarity: 134/361 - (37%)
• Gaps: 138/361 - (38%)

  Fly    50 LVAIVSIIGNVLVIIVFRRERKLRRRTNYYIVSLAMADLLVGALGIPFAILASMGLPRNLHACLF 114
            |:.:|..:||.||:.|..|..:....||.:|::|.:|||......:||            .|.::
Human    34 LIFLVGTVGNTLVLAVLLRGGQAVSTTNLFILNLGVADLCFILCCVPF------------QATIY 86

  Fly   115 TV------SLL------VVLCTI--SIFCLVAVSVDRYWAILYPMAYSRNVRT-RTAIFIISMCW 164
            |:      |||      ::..|:  |.|.|.|||:|||.||.||: :||.:|| |.|:..|.:.|
Human    87 TLDGWVFGSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPL-HSRELRTPRNALAAIGLIW 150

  Fly   165 VAGTIVGFLPLF---------------------GWHADVNHNQE-CLFVEVMDYNYLVFLYFATI 207
                  |...||                     .|.|......: |.||    ::||:
Human   151 ------GLSLLFSGPYLSYYRQSQLANLTVCHPAWSAPRRRAMDICTFV----FSYLL------- 198

  Fly   208 ITPALLMLAFYTHIYRVIIKQVRQIVTMNPASDLSRRSSAAVVQVTTPGRGGHTGTMLRVLGAAR 272
              |.|::...|....|.:.:.|..:..                     |.|            ||
Human   199 --PVLVLGLTYARTLRYLWRAVDPVAA---------------------GSG------------AR 228

  Fly   273 KRDVKATQNLSIIVLFFMICWIPLYTINCIKAFCPDCYVHPKLTLFCI---------------IL 322
            :...|.|:.:.|:...|.:||:|.:.:                 :.|:               ||
Human   229 RAKRKVTRMILIVAALFCLCWMPHHAL-----------------ILCVWFGQFPLTRATYALRIL 276

  Fly   323 SHL----NSAVNPVLYAYHLKDFRAALKNLLLKMMG 354
            |||    ||.|||::||...|.||...:.:...::|
Human   277 SHLVSYANSCVNPIVYALVSKHFRKGFRTICAGLLG 312

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AdoR	NP_651772.1	7tm_4	52..>220	CDD:304433	56/204 (27%)
		7tm_1	58..334	CDD:278431	79/331 (24%)
GALR2	NP_003848.1	7tm_4	32..>177	CDD:304433	47/161 (29%)
		7tm_1	42..292	CDD:278431	79/331 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910