DRSC/TRiP Functional Genomics Resources

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Protein Alignment AdoR and Gpr6

DIOPT Version :9

Sequence 1:NP_651772.1 Gene:AdoR / 43583 FlyBaseID:FBgn0039747 Length:774 Species:Drosophila melanogaster
Sequence 2:NP_113994.1 Gene:Gpr6 / 83683 RGDID:70939 Length:363 Species:Rattus norvegicus


Alignment Length:322 Identity:79/322 - (24%)
Similarity:135/322 - (41%) Gaps:57/322 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly    36 PSSELNIPYTVFEVLVAIVSII---GNVLVIIVFRRERKLRRRTNYYIVSLAMADLLVGALGIPF 97
            ||..|......::||:.:...:   .|.||:.:......||......:.|||.||||.|. |:..
  Rat    65 PSGLLLSAVNPWDVLLCVSGTVIAGENALVVALIASTPALRTPMFVLVGSLATADLLAGC-GLIL 128

  Fly    98 AILASMGLPRNLHACLFTVSLLVVLCTISIFC-----LVAVSVDRYWAILYPMA-YSRNVRTRTA 156
            ..:....:|..      |||||:|...::.|.     |:|::||||.::...:. |||  ||...
  Rat   129 HFVFQYVVPSE------TVSLLMVGFLVASFAASVSSLLAITVDRYLSLYNALTYYSR--RTLLG 185

  Fly   157 I-FIISMCWVAGTIVGFLPLFGWH--ADVNHNQECLFVEVMDYNYLVFLYFATIITPALLMLAFY 218
            : .:::..|.....:|.||:.||:  ||   ...|..|..:..:::..|..:..:... :||..|
  Rat   186 VHLLLAATWTVSLGLGLLPVLGWNCLAD---RASCSVVRPLTRSHVALLSTSFFVVFG-IMLHLY 246

  Fly   219 THIYRVIIKQVRQIVTMNPASDLSRRSSAAVVQVTTPGRGGHTGTMLRVLGAARKRDVKATQNLS 283
            ..|.:|:.:...||..        ::...|...:....:|  .||:..|||.             
  Rat   247 VRICQVVWRHAHQIAL--------QQHCLAPPHLAATRKG--VGTLAVVLGT------------- 288

  Fly   284 IIVLFFMICWIPLYTINCIKAFCPDCYVHPKLTLFCIILSHLNSAVNPVLYAYHLKDFRAAL 345
                 |...|:| :.|.|:.....|..::...||   :.:..||.:||::||:..::.:.||
  Rat   289 -----FGASWLP-FAIYCVVGSQEDPAIYTYATL---LPATYNSMINPIIYAFRNQEIQRAL 341

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
AdoRNP_651772.1 7tm_4 52..>220 CDD:304433 47/179 (26%)
7tm_1 58..334 CDD:278431 70/284 (25%)
Gpr6NP_113994.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 28..51
7tm_GPCRs 74..341 CDD:421689 74/311 (24%)
TM helix 1 75..101 CDD:410628 5/25 (20%)
TM helix 2 108..133 CDD:410628 9/25 (36%)
TM helix 3 142..172 CDD:410628 11/29 (38%)
TM helix 4 184..204 CDD:410628 2/19 (11%)
TM helix 5 223..252 CDD:410628 5/29 (17%)
TM helix 6 273..303 CDD:410628 11/50 (22%)
TM helix 7 309..334 CDD:410628 8/27 (30%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
21.910

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