Protein Alignment AdoR and GPR101

DIOPT Version :9

• Sequence 1: NP_651772.1
• Gene: AdoR / 43583
• FlyBaseID: FBgn0039747
• Length: 774
• Species: Drosophila melanogaster
• Sequence 2: NP_473362.1
• Gene: GPR101 / 83550
• HGNCID: 14963
• Length: 508
• Species: Homo sapiens
• Alignment Length: 511
• Identity: 106/511 - (20%)
• Similarity: 187/511 - (36%)
• Gaps: 172/511 - (33%)

  Fly    24 ATTSKDAKDSDS-----PSSELNIPY-------TVFEVLVAIVSIIGNVLVIIVFRRERKLRRRT 76
            :|.:...::|:|     |.|::.|..       ||..:.:| .|.:||:::.:|.:|:.:|.:.|
Human     3 STCTNSTRESNSSHTCMPLSKMPISLAHGIIRSTVLVIFLA-ASFVGNIVLALVLQRKPQLLQVT 66

  Fly    77 NYYIVSLAMADLLVGALGIPFAILASMGL--PRNLHACLFTVSLLVVLCTISIFCLVAVSVDRYW 139
            |.:|.:|.:.|||..:|..|:.:..|:.|  |.|.|.|...|||..:....|:..:|.||||||.
Human    67 NRFIFNLLVTDLLQISLVAPWVVATSVPLFWPLNSHFCTALVSLTHLFAFASVNTIVVVSVDRYL 131

  Fly   140 AILYPMAYSRNVRTRTAIFIISMCWVAGTIVGFLPLFGW--HADVNHNQECLFVEVMDYNYLVFL 202
            :|::|::|...:..|....::...|:...:....||:||  .|....|..|..:.....:|.:..
Human   132 SIIHPLSYPSKMTQRRGYLLLYGTWIVAILQSTPPLYGWGQAAFDERNALCSMIWGASPSYTILS 196

  Fly   203 YFATIITPALLMLAFYTHIYRVIIKQVRQIVTMNPASDLSRRSSAAVVQVTTPGRGGHTGTMLRV 267
            ..:.|:.|.::|:|.|:.::..                 :||..|.:..|
Human   197 VVSFIVIPLIVMIACYSVVFCA-----------------ARRQHALLYNV--------------- 229

  Fly   268 LGAARKRDVKATQNLSIIVLFFMICWIPLYTINCIKAFCPDCYVHPKLTLFCIILSHLNSAVNPV 332
                 ||     .:|.:.|                    .||..:
Human   230 -----KR-----HSLEVRV--------------------KDCVEN-------------------- 244

  Fly   333 LYAYHLKDFRAALKNLLLKMMGVDIDQQAE--AIHRFSV-ASQHRLQSMDSNMRSTQPRLYVGEY 394
                  :|...|.|.       .:...::|  ..|...| |.:.|:::.|.::::.:......|
Human   245 ------EDEEGAEKK-------EEFQDESEFRRQHEGEVKAKEGRMEAKDGSLKAKEGSTGTSE- 295

  Fly   395 SPIWLRQQQEALKNSQLLPKCGVVSPCFNNINQTVAAVASV-----TTDLEREMWNIVEASSG-- 452
            |.:..|..:|..::|                  |||:..|:     :|.:|.   |.::|..|
Human   296 SSVEARGSEEVRESS------------------TVASDGSMEGKEGSTKVEE---NSMKADKGRT 339

  Fly   453 ------AELGETSYEF-----------------PSPAPGSQRSSERNSSSTVPPAP 485
                  .:|||...||                 |...|.|:|:|..|     ||.|
Human   340 EVNQCSIDLGEDDMEFGEDDINFSEDDVEAVNIPESLPPSRRNSNSN-----PPLP 390

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AdoR	NP_651772.1	7tm_4	52..>220	CDD:304433	51/171 (30%)
		7tm_1	58..334	CDD:278431	59/279 (21%)
GPR101	NP_473362.1	7tm_1	48..>222	CDD:278431	50/190 (26%)
		FCP1_C	<243..334	CDD:286402	21/145 (14%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	244..338		22/148 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	476..508

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910