DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AdoR and Lpar3

DIOPT Version :9

Sequence 1:	NP_651772.1	Gene:	AdoR / 43583	FlyBaseID:	FBgn0039747	Length:	774	Species:	Drosophila melanogaster
Sequence 2:	XP_006233531.1	Gene:	Lpar3 / 66025	RGDID:	620565	Length:	354	Species:	Rattus norvegicus

Alignment Length:	347	Identity:	80/347 - (23%)
Similarity:	145/347 - (41%)	Gaps:	62/347 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 VAIVSIIG----------NVLVIIVFRRERKLRRRTNYYIVSLAMADLLVGALGIPFAILASMGL 105
            :.||..:|          |.|||......||......|.:.:||.||...| :...|.:..:..:
  Rat    30 LVIVLCVGTFFCLFIFFSNSLVIAAVITNRKFHFPFYYLLANLAAADFFAG-IAYVFLMFNTGPV 93

  Fly   106 PRNL--HACLFTVSLLVVLCTISIFCLVAVSVDRYWAILYPMAYSRNVRTRTAIFIISMCWVAGT 168
            .:.|  :..|....||....|.|:..|:.::|:|:.:|:....:|...:.|..:.|: :.|....
  Rat    94 SKTLTVNRWLLRQGLLDTSLTASLANLLVIAVERHMSIMRMRIHSNLTKKRVTLLIL-LVWAIAI 157

  Fly   169 IVGFLPLFGWHADVNHNQECLFVEVMDYNYLVFLYFATIITPALLMLAFYTHIYRVIIKQVRQIV 233
            .:|.:|..||:...|.:.......:...:||:|...:.::. ..:|:..|..|| :.:|:...::
  Rat   158 FMGAVPTLGWNCLCNISACSSLAPIYSRSYLIFWTVSNLLA-FFIMVVVYVRIY-MYVKRKTNVL 220

  Fly   234 TMNPASDLSRRSSAAVVQVTTPGRGGHTGTMLRVLGAARKRDVKATQNLSIIVLFFMICWIPLYT 298
            :.:.:..:|||.:...:.          .|::.||||                  |::||.|...
  Rat   221 SPHTSGSISRRRAPMKLM----------KTVMTVLGA------------------FVVCWTPGLV 257

  Fly   299 INCIKAF-CPDCYV-HPKLTLFCIILSHLNSAVNPVLYAYHLKDFRAALKNLLLKMM-GVDIDQQ 360
            :..:... |..|.| |.|  .:.::|:.|||.:||::|:|..:|    :.|.:.||: ....|..
  Rat   258 VLLLDGLNCKQCNVQHVK--RWFLLLALLNSVMNPIIYSYKDED----MYNTMRKMICCAPHDSN 316

  Fly   361 AE--------AIH-RFSVASQH 373
            ||        .|| |....||:
  Rat   317 AERHPSRIPSTIHSRSDTGSQY 338

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AdoR	NP_651772.1	7tm_4	52..>220	CDD:304433	40/179 (22%)
AdoR	NP_651772.1	7tm_1	58..334	CDD:278431	64/289 (22%)
Lpar3	XP_006233531.1	7tmA_LPAR3_Edg7	31..304	CDD:320465	70/310 (23%)
		TM helix 1	33..57	CDD:320465	6/23 (26%)
		TM helix 2	66..87	CDD:320465	7/21 (33%)
		TM helix 3	103..125	CDD:320465	6/21 (29%)
		TM helix 4	147..163	CDD:320465	3/16 (19%)
		TM helix 5	184..207	CDD:320465	4/23 (17%)
		TM helix 6	238..260	CDD:320465	9/49 (18%)
		TM helix 7	272..297	CDD:320465	10/26 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910